Therapeutic Drug Monitoring: Techniques and Applications in Pharmaceutical Analysis
A special issue of Pharmaceuticals (ISSN 1424-8247).
Deadline for manuscript submissions: 25 January 2026 | Viewed by 71
Special Issue Editors
2. Toxicological and Antidoping Center, Faculty of Pharmacy, Comenius University Bratislava, Odbojarov 10, 832 32 Bratislava, Slovakia
Interests: CE-MS/MS; LC-MS/MS; green analytical methods; method development; therapeutic drug monitoring; bioanalytical method validation; antibiotics; Janus kinase inhibitors; pharmacokinetics
2. Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic
3. Toxicological and Antidoping Center, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic
Interests: capillary electrophoresis; liquid chromatography; mass spectrometry; biologics; therapeutic drug monitoring; bioanalysis; quality control; therapeutic peptides
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Special Issue Information
Dear Colleagues,
Therapeutic Drug Monitoring (TDM) is an essential part of modern pharmacotherapy, allowing for the individualization of drug dosing through the measurement of drug concentrations in biological matrices such as blood, plasma, or saliva. It is particularly important for medications with a narrow therapeutic window, high interindividual variability, or a risk of significant toxicity. In recent years, advances in analytical technologies have greatly enhanced the precision, sensitivity, and speed of TDM workflows.
This Special Issue welcomes a wide range of contributions that reflect the interdisciplinary nature of TDM. We are especially interested in studies focused on the development and validation of analytical methods, innovative sample preparation strategies, and bioanalytical challenges. Equally, we invite submissions addressing pharmacokinetic and pharmacodynamic modeling, individualized dosing strategies, and the application of TDM in special patient populations. Research exploring how TDM supports personalized and precision medicine is particularly encouraged.
By bringing together pharmaceutical scientists, clinicians, and analytical chemists, this Special Issue aims to provide a comprehensive overview of current trends and innovations in TDM, and to showcase its impact on safer and more effective drug therapy.
Dr. Ivana Cizmarova
Dr. Juraj Piestansky
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Therapeutic Drug Monitoring (TDM)
- bioanalytical method development
- LC-MS/MS
- sample preparation
- method validation
- pharmacokinetics
- pharmacodynamics
- individualized dosing
- precision medicine
- clinical applications
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