Management and Treatment of Cardiometabolic Disorders Across the Lifespan
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".
Deadline for manuscript submissions: 5 October 2026 | Viewed by 229
Special Issue Editors
Interests: frailty; cardiometabolic disorders; insulin resistance; prediabetes; diabetes
Special Issues, Collections and Topics in MDPI journals
Interests: cardiometabolic disorders; diabetes; prediabetes; frailty; plastic surgery
Special Issue Information
Dear Colleagues,
Cardiometabolic disorders encompass a spectrum of interrelated conditions including metabolic syndrome, obesity, type 2 diabetes mellitus, hypertension, dyslipidemia, chronic kidney disease (CKD), and atherosclerotic cardiovascular disease (ASCVD). These disorders share overlapping pathophysiological pathways—primarily driven by insulin resistance, ectopic adiposity, and chronic inflammation—that link cardiovascular, renal, and metabolic health. The interconnectedness of these systems means that dysfunction in one often accelerates pathology in the others, necessitating integrated management strategies. Pharmacological and surgical management are indicated when lifestyle interventions are insufficient or when comorbidities are present. Pharmacotherapies include sodium–glucose cotransporter-2 (SGLT2) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, mineralocorticoid receptor antagonists, and combination therapies, which target multiple pathophysiological pathways and are particularly effective in patients with diabetes, CKD, and ASCVD. Individualized pharmacological treatment is necessary, especially for metabolic syndrome components such as hypertension, dyslipidemia, and hyperglycemia. For obesity, both non-surgical (e.g., intensive lifestyle, pharmacotherapy) and surgical weight loss strategies (e.g., bariatric surgery) may be considered, with selection based on severity, comorbidities, and patient preference. Both clinical and preclinical papers are welcome.
Dr. Pasquale Mone
Dr. Maria Luisa D’Onghia
Dr. Luigi Simone Aversa
Guest Editors
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Keywords
- cardiometabolic disorders
- frailty
- diabetes
- prediabetes
- insulin resistance
- hypertension
- atherosclerotic cardiovascular disease
- obesity
- metabolic syndrome
- plastic surgery
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