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Nutrients
Special Issues
Causes and Consequences of Digestive Diseases on Nutritional Status
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Causes and Consequences of Digestive Diseases on Nutritional Status

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: closed (10 March 2021) | Viewed by 22923

Special Issue Editors

Prof. Dr. Miguel Montoro

E-Mail Website
Guest Editor
1. Gastroenterology, Hepatology and Nutrition Unit, University Hospital San Jorge, 22004 Huesca, Spain
2. Department of Medicine, Faculty of Health and Sport Sciences, University of Zaragoza, 22002 Huesca, Spain
3. Aragon Health Research Institute (IIS Aragón), 50009 Zaragoza, Spain
Interests: nutritional management; nutritional support; motility disorders; malabsorption; inflammatory bowel disease; celiac disease
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Alberto Lue

E-Mail Website
Guest Editor
Service of Digestive Diseases, University Clinic Hospital Lozano Blesa, Institute for Health Research Aragón (IIS-Aragón), Zaragoza, Spain
Interests: nutritional management; nutritional support; motility disorders; malabsorption; inflammatory bowel disease; celiac disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In 1917, the Academy of Nutrition declared that “registered dietitian nutritionists (RDNs) should play a significant role in educating medical students, fellows, and physicians in practice and that the more physicians learn about the effectiveness of nutrition for the prevention and treatment of diseases, the more likely they are to consult with RDNs and understand and value the role of RDNs in improving the quality of care provided to patients”. On the other hand, RDNs should be aware of the mechanisms by which diseases can lead to the deterioration of nutritional status (either by excess or by default). Physicians need to have a reliable ally for the nutritional management of their patients, but this is only possible if the dietitian nutritionist demonstrates a robust knowledge about the causes and consequences of diseases on nutritional status.

The aim of this Special Issue is to update knowledge on the pathogenesis of nutritional alterations commonly observed in gastroenterological, hepatobiliary, and pancreatic diseases, and due to its global vision, it aspires to be useful both to RDNs and to family doctors, gastroenterologist, internists, and surgeons.

Finally, this special topic supports interprofessional education in nutrition as an essential component of medical education.

Prof. Dr. Miguel Montoro
Prof. Dr. Alberto Lue
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutrition
  • motor disorders of the esophagus
  • caustics
  • gastroesophageal reflux disease
  • pernicious anemia
  • bariatric surgery
  • celiac disease
  • malabsorption
  • lactose
  • fructose
  • protein-losing gastroenteropathy
  • inflammatory bowel disease
  • short bowel syndrome
  • neurogastroenterology
  • pancreatic insufficiency
  • nonalcoholic fatty liver disease
  • liver and alcohol
  • complications of liver cirrhosis
  • colorectal cancer

Published Papers (3 papers)

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Review

24 pages, 403 KiB  
Review
Small and Large Intestine (II): Inflammatory Bowel Disease, Short Bowel Syndrome, and Malignant Tumors of the Digestive Tract
by Yolanda Ber, Santiago García-Lopez, Carla J. Gargallo-Puyuelo and Fernando Gomollón
Nutrients 2021, 13(7), 2325; https://doi.org/10.3390/nu13072325 - 6 Jul 2021
Cited by 12 | Viewed by 3448
Abstract
The small intestine is key in the digestion and absorption of macro and micronutrients. The large intestine is essential for the absorption of water, to allow adequate defecation, and to harbor intestinal microbiota, for which their nutritional role is as important as it [...] Read more.
The small intestine is key in the digestion and absorption of macro and micronutrients. The large intestine is essential for the absorption of water, to allow adequate defecation, and to harbor intestinal microbiota, for which their nutritional role is as important as it is unknown. This article will describe the causes and consequences of malnutrition in patients with inflammatory bowel diseases, the importance of screening and replacement of micronutrient deficits, and the main indications for enteral and parenteral nutrition in these patients. We will also discuss the causes of short bowel syndrome, a complex entity due to anatomical or functional loss of part of the small bowel, which can cause insufficient absorption of liquid, electrolytes, and nutrients and lead to complex management. Finally, we will review the causes, consequences, and management of malnutrition in patients with malignant and benign digestive tumors, including neuroendocrine tumors (present not only in the intestine but also in the pancreas). Full article
(This article belongs to the Special Issue Causes and Consequences of Digestive Diseases on Nutritional Status)
25 pages, 7594 KiB  
Review
Impact of Liver and Pancreas Diseases on Nutritional Status
by Pablo Cañamares-Orbis, Vanesa Bernal-Monterde, Olivia Sierra-Gabarda, Diego Casas-Deza, Guillermo Garcia-Rayado, Luis Cortes and Alberto Lué
Nutrients 2021, 13(5), 1650; https://doi.org/10.3390/nu13051650 - 13 May 2021
Cited by 8 | Viewed by 3558
Abstract
Liver and pancreatic diseases have significant consequences on nutritional status, with direct effects on clinical outcomes, survival, and quality of life. Maintaining and preserving an adequate nutritional status is crucial and should be one of the goals of patients with liver or pancreatic [...] Read more.
Liver and pancreatic diseases have significant consequences on nutritional status, with direct effects on clinical outcomes, survival, and quality of life. Maintaining and preserving an adequate nutritional status is crucial and should be one of the goals of patients with liver or pancreatic disease. Thus, the nutritional status of such patients should be systematically assessed at follow-up. Recently, great progress has been made in this direction, and the relevant pathophysiological mechanisms have been better established. While the spectrum of these diseases is wide, and the mechanisms of the onset of malnutrition are numerous and interrelated, clinical and nutritional manifestations are common. The main consequences include an impaired dietary intake, altered macro and micronutrient metabolism, energy metabolism disturbances, an increase in energy expenditure, nutrient malabsorption, sarcopenia, and osteopathy. In this review, we summarize the factors contributing to malnutrition, and the effects on nutritional status and clinical outcomes of liver and pancreatic diseases. We explain the current knowledge on how to assess malnutrition and the efficacy of nutritional interventions in these settings. Full article
(This article belongs to the Special Issue Causes and Consequences of Digestive Diseases on Nutritional Status)
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36 pages, 2885 KiB  
Review
Small and Large Intestine (I): Malabsorption of Nutrients
by Miguel A. Montoro-Huguet, Blanca Belloc and Manuel Domínguez-Cajal
Nutrients 2021, 13(4), 1254; https://doi.org/10.3390/nu13041254 - 11 Apr 2021
Cited by 38 | Viewed by 15074
Abstract
Numerous disorders can alter the physiological mechanisms that guarantee proper digestion and absorption of nutrients (macro- and micronutrients), leading to a wide variety of symptoms and nutritional consequences. Malabsorption can be caused by many diseases of the small intestine, as well as by [...] Read more.
Numerous disorders can alter the physiological mechanisms that guarantee proper digestion and absorption of nutrients (macro- and micronutrients), leading to a wide variety of symptoms and nutritional consequences. Malabsorption can be caused by many diseases of the small intestine, as well as by diseases of the pancreas, liver, biliary tract, and stomach. This article provides an overview of pathophysiologic mechanisms that lead to symptoms or complications of maldigestion (defined as the defective intraluminal hydrolysis of nutrients) or malabsorption (defined as defective mucosal absorption), as well as its clinical consequences, including both gastrointestinal symptoms and extraintestinal manifestations and/or laboratory abnormalities. The normal uptake of nutrients, vitamins, and minerals by the gastrointestinal tract (GI) requires several steps, each of which can be compromised in disease. This article will first describe the mechanisms that lead to poor assimilation of nutrients, and secondly discuss the symptoms and nutritional consequences of each specific disorder. The clinician must be aware that many malabsorptive disorders are manifested by subtle disorders, even without gastrointestinal symptoms (for example, anemia, osteoporosis, or infertility in celiac disease), so the index of suspicion must be high to recognize the underlying diseases in time. Full article
(This article belongs to the Special Issue Causes and Consequences of Digestive Diseases on Nutritional Status)
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