Nutritional Bioactive Compounds and Diabetic Neuropathy
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".
Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 5027
Special Issue Editor
Special Issue Information
Dear Colleagues,
Diabetes mellitus is a true social and health problem throughout the world. Approximately 460 million people suffer from diabetes mellitus. Long-term complications involve the vascular system, both in arteries (macroangiopathy) and in small vessels (diabetic microangiopathy), among which are those of the retina, kidney and nervous tissue (diabetic neuropathy).
Diabetic neuropathy affects both peripheral (legs, feet), visceral and central nervous tissue (including retina). This damage is generated by long-term high glucose levels; however, despite being a direct alteration of the nervous tissue, there is no doubt that the involvement of the blood vessels is a factor that jointly affects the nervous tissue.
Oxidative stress is one of the main mechanisms that initiate and promote the evolution of diabetic neuropathy. For this reason, in addition to the intensive control of blood glucose levels, antioxidants are postulated as possible useful compounds in the prevention of said neuropathy.
Diet is not only useful to control blood glucose levels, but it is also a source of antioxidant compounds, which have been shown to be effective in preventing cardiovascular disease, including type 2 diabetes mellitus.
In this Special Issue, we encourage investigators to contribute original research and review articles that address biochemical, functional and clinical evidence, which provide a greater understanding of the role that various nutrients can play in the pathophysiology and evolution of diabetic neuropathy.
Dr. José Pedro De La Cruz Cortes
Guest Editor
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Keywords
- diabetes
- neuropathy
- antioxidants
- bioactive compounds
- micronutrients
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