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Dietary Phytochemicals and Health Benefits: Epidemiological Evidence

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A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: closed (15 March 2023) | Viewed by 5688

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Special Issue Editor

Prof. Dr. Kyong Park

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Guest Editor

Department of Food and Nutrition, Yeungnam University, Gyeongsan 38541, Republic of Korea
Interests: mercury; selenium; antioxidants; phytochemicals; amino acids; diabetes; CVD; epidemiology; Dietary Index; cohort

Special Issue Information

Dear Colleagues,

Phytochemicals are plant-derived substances with various known health benefits. Wheat grains contain various nutrients and physiologically active substances, including powerful antioxidants (phenolic acids, flavonoids, carotenoids, vitamin E, and phytosterols) as well as water-soluble β-glucan. Vegetables and fruits contain large amounts of vitamins and minerals, dietary fibers, carotenoids, and flavonoids. Nuts, legumes, olives, and other plant foods are also rich in various phytochemicals. A balanced diet of various plant foods provides several types of phytochemicals, and the combination of vitamins, minerals, and non-nutrients may offer synergistic benefits.

The goal of this Special Issue, “The Dietary Phytochemicals and Health Benefits: Epidemiological Evidence”, is to showcase scientific evidence from epidemiological studies that evaluate the association between dietary phytochemicals and human health and investigate the diverse phytochemical-related prevention pathways. Both original and review articles are welcome, especially epidemiological studies and meta-analyses.

Prof. Dr. Kyong Park
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

dietary
phytochemicals
plant foods
chronic disease
human health
cohort
epidemiology
meta-analysis

Published Papers (3 papers)

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Editorial

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3 pages, 194 KiB

Open AccessEditorial

The Role of Dietary Phytochemicals: Evidence from Epidemiological Studies

by Kyong Park

Nutrients 2023, 15(6), 1371; https://doi.org/10.3390/nu15061371 - 12 Mar 2023

Viewed by 1646

Abstract

Phytochemicals are biologically active substances derived from plants that play various roles in the human body [...] Full article

(This article belongs to the Special Issue Dietary Phytochemicals and Health Benefits: Epidemiological Evidence)

Research

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11 pages, 603 KiB

Open AccessArticle

Association between Phytochemical Index and Osteoporosis in Women: A Prospective Cohort Study in Korea

by Hyeonji Yoo and Kyong Park

Nutrients 2023, 15(7), 1605; https://doi.org/10.3390/nu15071605 - 25 Mar 2023

Cited by 1 | Viewed by 1568

Abstract

Osteoporosis is a prevalent issue among postmenopausal women, who have a higher incidence of the condition than men. This study aimed to examine the relationship between phytochemical-rich food intake and osteoporosis incidence in premenopausal and postmenopausal women. The data analyzed included 4600 women aged 40–69 who were free of osteoporosis at baseline, with dietary intake evaluated through a semi-quantitative food frequency questionnaire and osteoporosis prevalence determined using interviewer-administered questionnaires and bone mineral density tests. The phytochemical index (PI) was calculated to reflect the intake levels of phytochemical-rich foods. Postmenopausal women in the highest PI quartile had a 16% lower risk of osteoporosis (95% confidence interval (CI): 0.71 to 0.99, p for trend = 0.02) than those in the lowest quartile, while no significant association was observed among premenopausal women (hazard ratio: 0.98, 95% CI: 0.78 to 1.24, p for trend = 0.8). These findings suggest that consuming phytochemical-rich foods may have a protective effect against osteoporosis in postmenopausal women, offering valuable scientific insights. However, additional research is needed to validate these findings using biochemical data. Overall, this study highlights the potential of dietary interventions to reduce the risk of osteoporosis in postmenopausal women. Full article

(This article belongs to the Special Issue Dietary Phytochemicals and Health Benefits: Epidemiological Evidence)

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14 pages, 641 KiB

Open AccessArticle

Prospective Associations between Cumulative Average Intake of Flavonoids and Hypertension Risk in the CArdioVascular Disease Association Study (CAVAS)

by Ji-Sook Kong, Yu-Mi Kim, Hye-Won Woo, Min-Ho Shin, Sang-Baek Koh, Hyeon-Chang Kim, Jin-Ho Shin and Mi-Kyung Kim

Nutrients 2023, 15(5), 1186; https://doi.org/10.3390/nu15051186 - 27 Feb 2023

Cited by 3 | Viewed by 2011

Abstract

In this study, we aimed to investigate the prospective associations and their shapes between the dietary intake of total flavonoids and their seven subclasses and hypertension risk in a prospective cohort, the KoGES_CArdioVascular disease Association Study (CAVAS), and to consider obesity status as an additional factor. A total of 10,325 adults aged 40 years and older were enrolled at baseline, and 2159 patients were newly diagnosed with hypertension during a median follow-up of 4.95 years. Cumulative dietary intake was estimated using a repeated food frequency questionnaire. Incidence rate ratios (IRRs) with 95% confidence intervals (CIs) were estimated using modified Poisson models with a robust error estimator. We observed nonlinear inverse associations between total and seven subclasses of flavonoids and hypertension risk, although there was no significant association between total flavonoids and flavones with hypertension risk in the highest quartile. For men, these inverse associations tended to be pronounced in the high BMI group, particularly for anthocyanins and proanthocyanidins [IRR (95% CI) in overweight/obese men: 0.53 (0.42–0.67) for anthocyanins; 0.55 (0.42–0.71) for proanthocyanidins]. Our results suggested that consumption of dietary flavonoids may not be dose-responsive but is inversely associated with hypertension risk, particularly among overweight/obese men. Full article

(This article belongs to the Special Issue Dietary Phytochemicals and Health Benefits: Epidemiological Evidence)

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