Health Benefit Assessment of Novel Ingredients and Diets
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition Methodology & Assessment".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 16
Special Issue Editors
Interests: foodomics; metabolomics; food science; advanced analytical techniques; food and health; mass spectrometry
Interests: simulation of gastrointestinal digestion; simulation of intestinal absorption; blood–brain barrier permeability; model animals
Special Issue Information
Dear Colleagues,
This Special Issue, ‘Health Benefit Assessment of Novel Ingredients and Diets’, aims to cover several key topics related to the impact of innovative food components and dietary patterns on human health. The main topics likely include the following: 1. The characterization of novel bioactive compounds with demonstrated relevance to human health through anti-inflammatory, antioxidant, antidiabetic, neuroprotective, or lipid-lowering mechanisms. 2. The development and application of physiologically relevant in vitro models to assess human digestion, absorption, metabolism, and health effects, such as static (e.g., INFOGEST) and dynamic (e.g., SHIME, TIM-1) in vitro digestion models, as well as intestinal cell models (e.g., Caco-2 cell line) for assessing nutrient transport and metabolisms. 3. Investigations to increase the bioaccessibility and bioavailability of bioactive compounds in humans, including encapsulation and delivery technologies (e.g., nanoencapsulation, liposomes) with demonstrated physiological relevance. 4. The utilization of microfluidic systems, such as lab-on-a-chip platforms to evaluate the nutritional impact of novel diets and ingredients. Emphasis should be placed on applications that provide insights into human physiology or disease prevention. 5. Applications of advanced in vivo and ex vivo models, including humanized animal models, organoids, and precision-cut tissue cultures, to evaluate the physiological effects of novel dietary compounds and their role in human health, particularly concerning gut microbiota, metabolic function, and chronic disease contexts.
Prof. Dr. Alejandro Cifuentes
Dr. Gloria Domínguez-Rodríguez
Guest Editors
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Keywords
- microfluidic systems
- organ-on-chip digestion models
- static digestion
- dynamic digestion
- in vivo models
- humanized animal models
- ex vivo tissue
- metabolism
- transport
- encapsulation
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