The Role of Dietary Bioactives in Bowel Health
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".
Deadline for manuscript submissions: closed (15 August 2025) | Viewed by 626
Special Issue Editor
Interests: mental health; microbiome medicine; neuroscience; nutrition, metabolism, and health; population health; ageing; artificial and augmented intelligence; cancer research; traditional Chinese medicine; clinical trial; disorders of gut–brain interactions; functional food; acupuncture
Special Issue Information
Dear Colleagues,
The gastrointestinal (GI) system serves as a pivotal nexus between diet, metabolism, and immune regulation, playing a fundamental role in maintaining homeostasis and protecting against disease. Dietary bioactives, including phytochemicals, probiotics, prebiotics, polypeptides, polysaccharides, and micronutrients, exert profound effects on intestinal barrier integrity, gut microbiota composition, and inflammatory responses; they are key factors in the pathogenesis, management, and prevention of inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), colorectal cancer, and other gastrointestinal pathologies. These bioactives mediate their beneficial effects through the modulation of oxidative stress, immune homeostasis, gut barrier function, microbial dynamics, epithelial regeneration, and bile acid metabolism, thereby supporting both intestinal health and systemic metabolic balance, highlighting their therapeutic potential in GI health and disease prevention.
This Special Issue of Nutrients, titled “The Role of Dietary Bioactives in Bowel Health”, invites the submission of high-quality original studies and review articles. Topics of interest include the identification and characterization of dietary bioactives and their metabolites in the context of bowel health, with a focus on the molecular mechanisms underlying their effects on gut microbiota, immune modulation, inflammation, intestinal barrier integrity, epithelial regeneration, and bile acid metabolism, as well as nutritional strategies for managing IBD, IBS, colorectal cancer, and other gastrointestinal disorders to support bowel health and disease prevention.
We look forward to receiving your valuable contributions to this Special Issue.
Dr. Linda Zhong
Guest Editor
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Keywords
- dietary bioactives
- bowel health
- inflammatory bowel disease
- irritable bowel syndrome
- colorectal cancer
- nutritional strategies
- immune modulation
- intestinal barrier integrity
- gut microbiota
- bile acid metabolism
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