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Special Issue "Nutritional Management of Diarrhea"

A special issue of Nutrients (ISSN 2072-6643).

Deadline for manuscript submissions: 15 July 2019.

Special Issue Editors

Guest Editor
Prof. Dr. Luzia Valentini

Department of Agriculture and Food Technology, Section of Dietetics, University of Applied Sciences, Neubrandenburg, Germany
Website | E-Mail
Interests: adult nutrition; liver cirrhosis; inflammatory bowel diseases; intestinal microbiota; intestinal permeability; clinical nutrition; medical nutrition therapy; RCT
Guest Editor
Dr. Christina N. Katsagoni

Department of Nutrition & Dietetics, School of Health Sciences and Education, Harokopio University, 70 El. Venizelou str.,176 71 Athens, Greece
Website | E-Mail
Interests: NAFLD; fatty liver; Mediterranean diet; Mediterranean lifestyle; paediatrics; cystic fibrosis; IBD; celiac disease; SBS; RCT
Guest Editor
Dr. Paula Crespo-Escobar

Unit of Celiac Disease and Immunopathology Dig, Health Research Institute La Fe, Spain; Dietitian and Researcher of Prevent CD and MyCyFAPP European Projects
Website | E-Mail
Interests: celiac disease; gastrointestinal disorders; paediatrics; nutrition; intestinal bowel syndrome; early nutrition; cystic fibrosis

Special Issue Information

Dear Colleagues,

As core group of the European Specialist Dietetic Network (ESDN) in Gastroenterology of the European Federation of Association (EFAD) we are pleased to invite you to actively contribute to the special issue on the nutritional management of diarrhea. We approach specialist dietitians, medical doctors, researchers and pharmacists to tackle this issue together from different perspectives. We aim at high quality, evidence-based and practice-oriented publications on dietary strategies to prevent or treat diarrhea in children or adults in a broad range of settings from otherwise healthy persons suffering from traveler diarrhea to severely ill patients in the intensive care environment, as well as the latest advances in the treatment of diarrhea associated conditions or diseases.

We are looking forward to starting this exciting journey with you.

Prof. Dr. Luzia Valentini
Dr. Christina N. Katsagoni
Dr. Paula Crespo-Escobar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Diarrhea associated conditions or diseases
  • Nutritional therapy / management /strategies
  • Novel therapies
  • Clinical evidence
  • Human, pediatric
  • Human, adults

Published Papers (1 paper)

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Open AccessArticle
Rotavirus Double Infection Model to Study Preventive Dietary Interventions
Nutrients 2019, 11(1), 131; https://doi.org/10.3390/nu11010131
Received: 4 December 2018 / Revised: 27 December 2018 / Accepted: 7 January 2019 / Published: 10 January 2019
PDF Full-text (1321 KB) | HTML Full-text | XML Full-text | Supplementary Files
Rotaviruses are the main cause of acute diarrhea among young children worldwide with an increased frequency of reinfection. Several life style factors, such as dietary components, may influence such processes by affecting the outcome of the first rotavirus infection and therefore having a [...] Read more.
Rotaviruses are the main cause of acute diarrhea among young children worldwide with an increased frequency of reinfection. Several life style factors, such as dietary components, may influence such processes by affecting the outcome of the first rotavirus infection and therefore having a beneficial impact on the anti-rotavirus immune responses during any subsequent reinfections. The aim of this research was to develop a double-infection model in rat that mimics real-life clinical scenarios and would be useful in testing whether nutritional compounds can modulate the rotavirus-associated disease and immune response. Three experimental designs and a preventive dietary-like intervention were conducted in order to achieve a differential response in the double-infected animals compared to the single-infected ones and to study the potential action of a modulatory agent in early life. Diarrhea was only observed after the first infection, with a reduction of fecal pH and fever. After the second infection an increase in body temperature was also found. The immune response against the second infection was regulated by the preventive effect of the dietary-like intervention during the first infection in terms of specific antibodies and DTH. A rotavirus-double-infection rat model has been developed and is suitable for use in future preventive dietary intervention studies. Full article
(This article belongs to the Special Issue Nutritional Management of Diarrhea)

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