Dietary Modulation of the Gut–Brain Axis: Nutraceuticals, Extracellular Vesicles and Metabolic Perspective
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Neuro Sciences".
Deadline for manuscript submissions: 25 May 2026 | Viewed by 11
Special Issue Editors
2. High Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut-URJC), University Rey Juan Carlos (URJC), 28922 Alcorcón, Spain
Interests: lipidomics; metabolomics; colorectal cancer; extracelluar vesicles; nutraceuticals; antitumorals
Special Issues, Collections and Topics in MDPI journals
2. High Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut-URJC), University Rey Juan Carlos (URJC), 28922 Alcorcón, Spain
Interests: nutraceuticals; extracellular vesicles; chemotherapy; diets; colorectal cancer; tissue engineering; histology; myenteric plexus; IBS; gastrointestinal motility; gut-brain axis
2. High Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut-URJC), University Rey Juan Carlos (URJC), 28922 Alcorcón, Spain
Interests: nutraceuticals; diets; gut–brain axis; gastrointestinal motility; visceral pain; antitumorals; X-rays; functional foods; peripheral neuropathy; enteric neuropathy; monosodium glutamate; N-Acetylcysteine; cannabinoids; chemotherapy; LPS
Special Issue Information
Dear Collegues,
The gut–brain axis comprises crosstalk between the gut and the brain. On the one hand, the enteric nervous system releases several molecules such as neurotransmitters to regulate the gut functions. Conversely, the brain releases other neurotransmitters which may regulate the gut functions, establishing a bidirectional relationship between the gut and the brain.
Mechanisms for communication from the gut to the brain have been investigated and numerous of them are involved in dietary modulation.
Extracellular vesicles are nanoparticles released by cells from different origins, including probiotics, and they could also work as carriers of other compounds such as nutraceuticals. Both extracellular vesicles and nutraceuticals may be studied by metabolomics analysis in order to clarify their relationship with gut–brain axis mechanisms.
The aim of this Special Issue is to investigate molecules, such as extracellular vesicles derived from probiotics or nutraceuticals, and their influence on the gut–brain axis mechanisms. Metabolites derived from these molecules could modulate brain–gut axis crosstalk mechanisms.
This Special Issue welcomes original research articles, reviews, systematic reviews and meta-analyses.
Suggested themes include, but are not limited to, the following areas:
- Metabolomics of extracellular vesicles derived from probiotics and their impact on brain–gut axis mechanisms.
- Nutraceuticals and their impact on gut–brain axis mechanisms.
- Metabolites from dietary compounds and their impact on the mechanisms of the brain–gut axis.
Dr. Ortega Moreno Lorena
Dr. Laura López-Gómez
Guest Editors
Dr. Yolanda López-Tofiño
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- dietary modulation
- extracellular vesicles
- nutraceuticals
- gut–brain axis
- metabolomics
- metabolites
- mechanisms
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