Dietary Modulation of the Gut–Brain Axis: Nutraceuticals, Extracellular Vesicles and Metabolic Perspective

Dear Collegues,

The gut–brain axis comprises crosstalk between the gut and the brain. On the one hand, the enteric nervous system releases several molecules such as neurotransmitters to regulate the gut functions. Conversely, the brain releases other neurotransmitters which may regulate the gut functions, establishing a bidirectional relationship between the gut and the brain.

Mechanisms for communication from the gut to the brain have been investigated and numerous of them are involved in dietary modulation.

Extracellular vesicles are nanoparticles released by cells from different origins, including probiotics, and they could also work as carriers of other compounds such as nutraceuticals. Both extracellular vesicles and nutraceuticals may be studied by metabolomics analysis in order to clarify their relationship with gut–brain axis mechanisms.

The aim of this Special Issue is to investigate molecules, such as extracellular vesicles derived from probiotics or nutraceuticals, and their influence on the gut–brain axis mechanisms. Metabolites derived from these molecules could modulate brain–gut axis crosstalk mechanisms.

This Special Issue welcomes original research articles, reviews, systematic reviews and meta-analyses.

Suggested themes include, but are not limited to, the following areas:

- Metabolomics of extracellular vesicles derived from probiotics and their impact on brain–gut axis mechanisms.

- Nutraceuticals and their impact on gut–brain axis mechanisms.

- Metabolites from dietary compounds and their impact on the mechanisms of the brain–gut axis.

Dr. Ortega Moreno Lorena
Dr. Laura López-Gómez
Guest Editors

Dr. Yolanda López-Tofiño
Guest Editor Assistant

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