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Special Issue "Low FODMAP and Gluten Free Diet for the Treatment of Gastrointestinal Diseases"
Deadline for manuscript submissions: closed (15 December 2019).
Interests: gastroenterology disorders; FODMAP diet; non-celiac gluten sensitivity
Special Issues and Collections in MDPI journals
The role of diet in the management of functional gastrointestinal disorders (FGIDs) is relevant. Dietary modification of FODMAPs (fermentable oligosaccharides-disaccharides, monosaccharides and polyols) has been demonstrated to have significant effects in treating clinical manifestations of patients with irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBDs) (i.e., ulcerative colitis, Crohn’s disease) and could be used to support pharmaceutical therapy usually employed in the treatment of these diseases. The low FODMAP diet requires a trained nutritionist because of its complexity, personalized explanation, follow-up, and reintroduction. It is an effective approach, which improves symptoms such as abdominal pain, stool consistency, bloating, postprandial fullness, and epigastric pain. This diet may reduce the expression of proinflammatory markers (C-reactive protein and fecal calprotectin), play a role in the modulation of the gut microbiome, and may influence epigenetic changes. More data are needed to investigate the long-term effects of the low FODMAP diet on the microbiome and the nutritional status of the patients. There are no studies that correlate the low FODMAP diet with other gastrointestinal diseases (i.e., functional esophageal or duodenal disorders) and more studies are needed in this direction. At the same time, the gluten-free diet (GFD) demonstrated its efficacy in patients with unexplained gastrointestinal symptoms and its use. Nowadays, GFD is used in celiac disease, non-celiac gluten sensibility, and in different gastrointestinal and systemic pathologies. Together with a low FODMAP diet, GFD is the most used diet in medicine.
Research on this topic is widely requested to clarify their indications and potential side effects in the long term.
Dr. Luca Elli
Dr. Leda Roncoroni
Manuscript Submission Information
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- Low FODMAP diet
- Gluten-free diet
- IBS (irritable bowel syndrome)
- Gastrointestinal diseases