Prevention and Treatment of Liver Diseases by Dietary Habits and Lifestyle

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: 15 December 2024 | Viewed by 71

Special Issue Editors

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Guest Editor
Clinica Medica Cesare Frugoni, Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, Italy
Interests: nutrients; nuclear receptors; gut–liver axis; tumorigenesis; cholesterol and lipid metabolism
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Clinica Medica Cesare Frugoni, Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, Italy
Interests: nutrition; nutrigenomics; pathophysiology of the gut–liver axis; gastrointestinal; Mediterranean diet

Special Issue Information

Dear Colleagues,

Liver diseases are often associated with metabolic conditions, such as metabolic dysfunction-associated steatotic liver disease (MASLD). The definition of MASLD has been rebranded, shifting the definition of non-alcoholic fatty liver disease (NAFLD), and is now more representative of the clinical and metabolic heterogeneity characterizing patients presenting with the accumulation of excess fat in the liver in the presence of other cardiometabolic risk factors. Dietary habits and lifestyle have a critical impact on the pathogenesis of liver diseases. Evidence shows that a balanced diet together with moderate and regular exercise as adjuvant therapeutic strategies in these patients are successfully improving steatosis, inflammation, hepatocyte ballooning, and fibrosis, which can even lead to the development of hepatocellular carcinoma. The clinical and metabolic benefits of lifestyle management are mainly achieved via mechanisms encompassing nutrigenomics, gut microbiota modulation, improvement in mitochondrial dysfunctions and oxidative stress, and the inhibition of inflammatory pathways.

In this Special Issue, we aim to summarize the main evidence on dietary habits and lifestyle in the prevention and treatment of liver diseases, and we welcome reviews, perspectives, short communications, and original research to reinforce the critical importance of lifestyle intervention and comprehensive management in addressing this growing global health concern.

Dr. Marica Cariello
Dr. Raffaella Maria Gadaleta
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • liver diseases
  • lifestyle
  • dietary habits
  • nutrition

Published Papers

This special issue is now open for submission.
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