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The Role of Health Benefits of Plant Extracts in Reduction of Rescue Medication

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: 15 June 2025 | Viewed by 2550

Special Issue Editor


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Guest Editor
Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark
Interests: herbal remedies; plant extract; phytochemical

Special Issue Information

Dear Colleagues,

In recent years, the potential role of plant extracts in promoting human health and preventing chronic diseases has attracted the interest of researchers worldwide. It is well known that plants produce a variety of phytochemicals with unique physical and chemical properties. The properties of each phytochemical are responsible for unique chemical interactions with traditional and novel disease targets. The complexity level includes the use of the combination of phytochemicals present in the selected extract and how these phytochemicals produce a comprehensive pharmacological response.

It is widely believed that the consumption of natural compounds such as phytochemicals can prevent inflammation, oxidative stress, metabolic dysregulation, and vascular dysfunction, as well as reduce multiple risk factors for non-communicable diseases, including obesity, diabetes, cardiovascular and neurological diseases, and certain types of cancer. Based on these premises, there is an urgent need for research to evaluate the effects of plant extracts from different areas of knowledge. In addition, if more herbal extracts with anti-inflammatory effects are available, it is possible to reduce the use of rescue medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), paracetamol, and synthetic opioids.

In this Special Issue, we welcome studies on any of the above aspects to expand knowledge on the effects of phytochemicals and their enriched products (raw foods, processed foods, functional foods, food supplements, plant powders, plant by-products, medicinal plants) on human health and diseases.

Dr. Kaj Winther
Guest Editor

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Keywords

  • plant extracts
  • herbal remedies
  • phytochemicals
  • nutraceuticals
  • antioxidants
  • anti-inflammatory
  • bioactive compounds
  • functional foods
  • medicinal plants
  • inflammation
  • metabolism
  • cardiovascular diseases
  • diabetes
  • obesity
  • health effects
  • disease prevention
  • chronic diseases

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Published Papers (2 papers)

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Research

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12 pages, 880 KiB  
Article
Positive Effect of Lecithin-Based Delivery Form of Curcuma and Boswellia Extracts on Irritable Bowel Syndrome After COVID-19 Infection
by Attilio Giacosa, Gaetan Claude Barrile, Clara Gasparri, Simone Perna and Mariangela Rondanelli
Nutrients 2025, 17(4), 723; https://doi.org/10.3390/nu17040723 - 18 Feb 2025
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Abstract
Background: Post-COVID-19 irritable bowel syndrome (PCIBS) is a frequent finding and is frequently associated with enteral dysbiosis. This pilot study compared the effects of extracts from curcuma and boswellia on PCIBS and irritable bowel syndrome (IBS) in individuals who had never had [...] Read more.
Background: Post-COVID-19 irritable bowel syndrome (PCIBS) is a frequent finding and is frequently associated with enteral dysbiosis. This pilot study compared the effects of extracts from curcuma and boswellia on PCIBS and irritable bowel syndrome (IBS) in individuals who had never had a COVID-19 infection (controls). Methods: A total of 16 subjects with PCIBS and 28 controls with evidence of IBS gastrointestinal symptoms and with enteral dysbiosis were recruited and supplemented for 30 days with sunflower-lecithin-based formulations of extracts of Curcuma longa (500 mg) and Boswellia serrata (150 mg) b.i.d. and with low-FODMAP diet. Abdominal bloating, abdominal pain, enteral dysbiosis (as increased urinary indican), and the global assessment of efficacy (GAE) were evaluated at the end of the study. Results: In both cohorts, intra-cohort changes revealed a statistically significant (p < 0.05) reduction in bloating and abdominal pain. The GAE showed similar and relevant satisfactory rates in both groups. On the contrary, urinary indican values showed a significant decrease only in the IBS group. Conclusions: Supplementation with Curcuma and Boswellia has favorable effects on abdominal bloating and abdominal pain of subjects with PCIBS and with IBS, while enteral dysbiosis is significantly decreased only in patients with IBS. Additional studies are needed to confirm these preliminary findings and to clarify the reasons for the persistence of dysbiosis in PCIBS. Full article
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Review

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36 pages, 1895 KiB  
Review
Comprehensive Ethnopharmacological Analysis of Medicinal Plants in the UAE: Lawsonia inermis, Nigella sativa, Ziziphus spina-christi, Allium cepa, Allium sativum, Cymbopogon schoenanthus, Matricaria aurea, Phoenix dactylifera, Portulaca oleracea, Reichardia tingitana, Salvadora persica, Solanum lycopersicum, Trigonella foenum-graecum, Withania somnifera, and Ziziphus lotus
by Razan S. Almasri, Alaa S. Bedir and Seham M. Al Raish
Nutrients 2025, 17(3), 411; https://doi.org/10.3390/nu17030411 - 23 Jan 2025
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Abstract
The United Arab Emirates (UAE) is home to diverse indigenous medicinal plants traditionally used for centuries. This study systematically evaluates the pharmacological and nutritional potential of key medicinal plants, including Lawsonia inermis, Nigella sativa, Ziziphus spina-christi, Allium cepa, Allium [...] Read more.
The United Arab Emirates (UAE) is home to diverse indigenous medicinal plants traditionally used for centuries. This study systematically evaluates the pharmacological and nutritional potential of key medicinal plants, including Lawsonia inermis, Nigella sativa, Ziziphus spina-christi, Allium cepa, Allium sativum, Cymbopogon schoenanthus, Matricaria aurea, Phoenix dactylifera, Portulaca oleracea, Reichardia tingitana, Salvadora persica, Solanum lycopersicum, Trigonella foenum-graecum, Withania somnifera, and Ziziphus lotus. Comprehensive literature searches were conducted using PubMed, Scopus, and Web of Science to identify studies relevant to their nutritional and pharmacological uses. The findings highlight the therapeutic roles of these plants in managing global health challenges such as gastrointestinal diseases, and antimicrobial resistance through bioactive compounds like flavonoids, polyphenols, and antioxidants. Additionally, their contributions to nutrition, including essential vitamins and minerals, are emphasized for disease prevention and health promotion. While this research focuses on the UAE, the implications are globally relevant, as many of these plants are also found in traditional medicine across Asia, Africa, and Europe. Integrating these findings into global nutritional and healthcare systems offers potential solutions for pressing public health concerns, reduces reliance on synthetic pharmaceuticals, and promotes sustainable healthcare practices. This work is a valuable reference for researchers, healthcare professionals, and policymakers, bridging traditional knowledge and modern scientific applications globally. Full article
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