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Nutrients
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Maternal Nutritional Intake and Child Health
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Maternal Nutritional Intake and Child Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition in Women".

Deadline for manuscript submissions: closed (15 March 2024) | Viewed by 2325

Special Issue Editors

Prof. Dr. Jin Jing

E-Mail Website
Guest Editor
Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China
Interests: maternal and child health; autism spectrum disorder; clinical psychology; behavioral science
Dr. Buyun Liu

E-Mail Website
Guest Editor
Institute of Public Health Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China
Interests: maternal and child health; epidemiology; obesity-related chronic diseases
Special Issues, Collections and Topics in MDPI journals
Dr. Xin Wang

E-Mail Website
Co-Guest Editor
Key Laboratory of Brain, Cognition and Education Science, Ministry of Education, Institute for Brain Research and Rehabilitation and Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou 510631, China
Interests: maternal and child health; early screening tools of neurodevelopmental disorders; early life environmental factors of neurodevelopmental disorders

Special Issue Information

Dear Colleagues,

Maternal nutrition plays a pivotal role in shaping the health trajectory of the next generation. This Special Issue is dedicated to unraveling the intricate connections between maternal nutritional intake and child health outcomes. We aim to foster a comprehensive understanding of how a mother's diet and nutritional status before, during, and after pregnancy influence the long-term health, growth, and well-being of her offspring.

The scope of the Special Issue encompasses a wide range of topics, including but not limited to: (1) pre-conception nutrition and programming: Exploring how maternal nutrition prior to conception can affect fetal development, organ formation, and susceptibility to chronic diseases or neurodevelopment disorders in later life. (2) Nutrient intake during pregnancy: Investigating the impact of specific nutrients such as vitamins, minerals, essential fatty acids, and macronutrients on the fetal growth, early life brain plasticity, and early childhood development. (3) Breastfeeding and postpartum nutrition: Examining how maternal diet during the breastfeeding period influences the composition of breast milk, immune support for the infant, and the establishment of long-term dietary preferences.

We invite researchers, clinicians, and practitioners from various disciplines to contribute original research articles, reviews and meta-analyses to this Special Issue. By assembling a collection of cutting-edge research, this issue seeks to advance our understanding of the complex interplay between maternal nutrition and child health, with the ultimate goal of informing public health policies, clinical practices, and future research endeavors.

Prof. Dr. Jin Jing
Dr. Buyun Liu
Dr. Xin Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • maternal and child health
  • pre-conception
  • pregnancy
  • postpartum
  • nutrition

Published Papers (2 papers)

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Review

17 pages, 1574 KiB  
Review
Impact of Transgenerational Nutrition on Nonalcoholic Fatty Liver Disease Development: Interplay between Gut Microbiota, Epigenetics and Immunity
by Hong-Tai Tzeng and Wei-Chia Lee
Nutrients 2024, 16(9), 1388; https://doi.org/10.3390/nu16091388 - 3 May 2024
Viewed by 521
Abstract
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most prevalent pediatric liver disorder, primarily attributed to dietary shifts in recent years. NAFLD is characterized by the accumulation of lipid species in hepatocytes, leading to liver inflammation that can progress to steatohepatitis, fibrosis, [...] Read more.
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most prevalent pediatric liver disorder, primarily attributed to dietary shifts in recent years. NAFLD is characterized by the accumulation of lipid species in hepatocytes, leading to liver inflammation that can progress to steatohepatitis, fibrosis, and cirrhosis. Risk factors contributing to NAFLD encompass genetic variations and metabolic disorders such as obesity, diabetes, and insulin resistance. Moreover, transgenerational influences, resulting in an imbalance of gut microbial composition, epigenetic modifications, and dysregulated hepatic immune responses in offspring, play a pivotal role in pediatric NAFLD development. Maternal nutrition shapes the profile of microbiota-derived metabolites in offspring, exerting significant influence on immune system regulation and the development of metabolic syndrome in offspring. In this review, we summarize recent evidence elucidating the intricate interplay between gut microbiota, epigenetics, and immunity in fetuses exposed to maternal nutrition, and its impact on the onset of NAFLD in offspring. Furthermore, potential therapeutic strategies targeting this network are also discussed. Full article
(This article belongs to the Special Issue Maternal Nutritional Intake and Child Health)
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22 pages, 1041 KiB  
Review
Epigenetic Genome Modifications during Pregnancy: The Impact of Essential Nutritional Supplements on DNA Methylation
by Maciej W. Socha, Wojciech Flis and Mateusz Wartęga
Nutrients 2024, 16(5), 678; https://doi.org/10.3390/nu16050678 - 28 Feb 2024
Viewed by 1366
Abstract
Pregnancy is an extremely stressful period in a pregnant woman’s life. Currently, women’s awareness of the proper course of pregnancy and its possible complications is constantly growing. Therefore, a significant percentage of women increasingly reach for various dietary supplements during gestation. Some of [...] Read more.
Pregnancy is an extremely stressful period in a pregnant woman’s life. Currently, women’s awareness of the proper course of pregnancy and its possible complications is constantly growing. Therefore, a significant percentage of women increasingly reach for various dietary supplements during gestation. Some of the most popular substances included in multi-ingredient supplements are folic acid and choline. Those substances are associated with positive effects on fetal intrauterine development and fewer possible pregnancy-associated complications. Recently, more and more attention has been paid to the impacts of specific environmental factors, such as diet, stress, physical activity, etc., on epigenetic modifications, understood as changes occurring in gene expression without the direct alteration of DNA sequences. Substances such as folic acid and choline may participate in epigenetic modifications by acting via a one-carbon cycle, leading to the methyl-group donor formation. Those nutrients may indirectly impact genome phenotype by influencing the process of DNA methylation. This review article presents the current state of knowledge on the use of folic acid and choline supplementation during pregnancy, taking into account their impacts on the maternal–fetal unit and possible pregnancy outcomes, and determining possible mechanisms of action, with particular emphasis on their possible impacts on epigenetic modifications. Full article
(This article belongs to the Special Issue Maternal Nutritional Intake and Child Health)
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