Nutrients

Journal Browser

► Journal Browser

Vital Connections between Immunometabolism, Immunonutrition and Health/Disease: A Look into the Future

Share This Special Issue

Special Issue Editor

Special Issue Information

Dear Colleagues,

Immunometabolism and immunonutrition play crucial roles in promoting health and preventing disease, as they represent the vital interfaces between the immune, metabolic and nutritional systems. Understanding these aspects is fundamental to optimizing the prevention and treatment strategies for various health conditions, as an integrated approach considering immunometabolism and immunonutrition can significantly contribute to promoting a balanced and resilient immune response, which is essential for maintaining health and preventing diseases. This Special Issue will discuss the possible cellular mechanisms and physiologies involved in the relationship between nutrition, the immune system and health/disease.

Prof. Dr. Ronaldo Vagner Thomatieli-Santos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Benefits of Publishing in a Special Issue

Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.

Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.

Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.

External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.

e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

Download All Papers

Order results

Result details

Show export options Show export options

Select all

Export citation of selected articles as:

Research

11 pages, 718 KiB

Open AccessArticle

Protective Effects of Probiotics on Runners’ Mood: Immunometabolic Mechanisms Post-Exercise

by Edgar Tavares-Silva, Valdir de Aquino Lemos, Elias de França, Jean Silvestre, Samile Amorim dos Santos, Graziela Rosa Ravacci and Ronaldo Vagner Thomatieli-Santos

Nutrients 2024, 16(21), 3761; https://doi.org/10.3390/nu16213761 - 1 Nov 2024

Viewed by 2054

Abstract

Background: The gut–brain axis may mediate mood changes due to strenuous exercise. Therefore, probiotic supplementation may mitigate mood worsening. Purpose: The present study aims to evaluate the effect of probiotic supplementation on mood and immunometabolic parameters after a marathon. Materials and methods: Fourteen marathon runners were selected and divided into placebo and probiotic groups that were supplemented for 30 days. Before and after the marathon, mood (POMS) was assessed, and blood was collected for analysis of immunometabolic parameters. Statistical analysis was performed, and p < 0.05 was considered to determine statistically differences. Results: Tension decreased after the marathon in both groups. Vigor decreased only in the placebo group. Fatigue increased after the marathon in both groups. TMD increased after the marathon in placebo. The IL2/IL-4 ratio decreased in the probiotic group after the marathon compared to before and increased compared to the placebo group. The IL-10 increased after the marathon in placebo. TNF-α increased after the marathon in probiotics. The TNF-α/IL-10 ratio decreased after the marathon in both groups. LPS decreased in the probiotic group after the marathon compared to before and in the placebo group. Conclusions: Thirty days of probiotic supplementation attenuated the impact of marathons on mood worsening. The decrease in LPS in the probiotic group mediated the change in the pro/anti-inflammatory balance, indicating an immunometabolic mechanism by which the gut–brain axis impacts mood after strenuous exercise. Full article

(This article belongs to the Special Issue Vital Connections between Immunometabolism, Immunonutrition and Health/Disease: A Look into the Future)

► Show Figures

Figure 1

18 pages, 1821 KiB

Open AccessArticle

How Immunonutritional Markers Are Associated with Age, Sex, Body Mass Index and the Most Common Chronic Diseases in the Hospitalized Geriatric Population—A Cross Sectional Study

by Serena S. Stephenson, Ganna Kravchenko, Renata Korycka-Błoch, Tomasz Kostka and Bartłomiej K. Sołtysik

Nutrients 2024, 16(15), 2464; https://doi.org/10.3390/nu16152464 - 29 Jul 2024

Cited by 3 | Viewed by 1987

Abstract

The aim of this study was to assess the relationship of different chronic diseases with immunonutritional markers in the senior population. Methods: this study included 1190 hospitalized geriatric patients. The criteria to participate were ability to communicate, given consent and C-reactive protein (CRP) lower than 6 mg/dL. Results: the mean age of the study population was 81.7 ± 7.6 years. NLR (neutrophil-to-lymphocyte ratio), LMR (lymphocyte-to-monocyte ratio), MWR (monocyte-to-white blood cell ratio), SII (systemic immune–inflammation index), PNI (prognostic nutritional index) and CAR (C-reactive protein-to-albumin ratio) were related to age. NLR and MWR were higher, while LMR, PLR (platelet-to-lymphocyte ratio and SII were lower in men. All markers were related to BMI. NLR, LMR, LCR (lymphocyte-to-CRP ratio), MWR, PNI and CAR were related to several concomitant chronic diseases. In multivariate analyses, age and BMI were selected as independent predictors of all studied immunonutritional markers. Atrial fibrillation, diabetes mellitus and dementia appear most often in the models. PNI presented the most consistent statistical association with age, BMI and concomitant chronic diseases. Conclusions: this study reveals the pivotal role of aging and BMI in inflammatory marker levels and the association of immunonutritional markers with different chronic diseases. Atrial fibrillation seems to have the most dominant connection to the immunonutritional markers. Full article

(This article belongs to the Special Issue Vital Connections between Immunometabolism, Immunonutrition and Health/Disease: A Look into the Future)

► Show Figures

Journal Menu

Journal Browser

Vital Connections between Immunometabolism, Immunonutrition and Health/Disease: A Look into the Future

Share This Special Issue

Special Issue Editor

Special Issue Information

Keywords

Benefits of Publishing in a Special Issue

Published Papers (2 papers)

Research

Further Information

Guidelines

MDPI Initiatives

Follow MDPI