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Nutritional Support for Improving the Life Quality in Liver Disease

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: 5 January 2026 | Viewed by 27795

Special Issue Editor


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Guest Editor
1. Department of General Medicine, Niigata University School of Medicine, Niigata, Japan
2. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
Interests: liver tumor; hepatocellular carcinoma; gene therapy; nutrition; liver disease; multi-disciplinary collaboration
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Special Issue Information

Dear Colleagues,

Nutritional support for liver disease is essential for patients’ prognoses and quality of life. Therefore, knowledge and information around diet and nutrition may help physicians to treat cases of various liver diseases. For this purpose, we invite investigators from various fields, including physicians and nutritionists, to contribute original research articles, systematic reviews, mini-review articles that contribute towards this aim. In addition, manuscripts focusing on multi-disciplinary collaboration in nutritional support are also appreciated.

Dr. Kenya Kamimura
Guest Editor

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Keywords

  • diet
  • nutrition
  • liver disease
  • multi-disciplinary collaboration

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Published Papers (1 paper)

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Research

12 pages, 1261 KiB  
Article
Sex Differences in the Association Between the Korean Healthy Eating Index and Liver Enzymes Among Korean Adults
by Seong-Uk Baek and Jin-Ha Yoon
Nutrients 2025, 17(14), 2372; https://doi.org/10.3390/nu17142372 - 20 Jul 2025
Viewed by 27258
Abstract
Background/Objectives: Dietary quality plays a crucial role in maintaining liver function. In this study, we examined sex differences in the association between dietary quality and elevated liver enzyme levels in Korean adults. Methods: This study included a nationwide sample of 15,997 males and [...] Read more.
Background/Objectives: Dietary quality plays a crucial role in maintaining liver function. In this study, we examined sex differences in the association between dietary quality and elevated liver enzyme levels in Korean adults. Methods: This study included a nationwide sample of 15,997 males and 22,300 females in South Korea. Dietary assessment was performed using the Korean Healthy Eating Index (KHEI), an evidence-based dietary quality index that quantitatively reflects adherence to Korean dietary guidelines (range 0–100). Serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were measured, with individuals classified as having elevated AST or ALT levels when values were ≥40 IU/L or ≥35 IU/L, respectively. Logistic regression analysis was performed to examine the association between the KHEI and elevated AST or ALT levels stratified by sex. Odds ratios (ORs) and 95% confidence intervals (CIs) were determined. Results: Among the males, a 10-point increase in the KHEI score was inversely associated with the likelihood of having elevated AST (OR: 0.90; 95% CI: 0.85–0.96) and ALT (OR: 0.96; 95% CI: 0.92–1.00) levels, respectively. Among the females, there was no clear association between the KHEI and elevated AST (OR: 0.98; 95% CI: 0.91–1.05) or ALT (OR: 1.00; 95% CI: 0.95–1.05) levels. Conclusion: Further research is warranted to elucidate the underlying mechanisms of the observed sex-specific associations and guide the development of targeted dietary interventions for liver health in males and females. Full article
(This article belongs to the Special Issue Nutritional Support for Improving the Life Quality in Liver Disease)
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