Effect of Dietary Nutrient Intake on Muscle Health in Older Adults
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".
Deadline for manuscript submissions: closed (5 March 2026) | Viewed by 152
Editor
Special Issue Information
Dear Colleagues,
Sarcopenia, the age-related decline in muscle mass and function, is increasingly understood as more than just a consequence of current nutrient intake in the elderly. It also stems from complex genetic and epigenetic regulatory processes throughout life.
Aging muscle exhibits anabolic resistance, meaning it responds less effectively to stimuli like protein and exercise. Beyond high-protein diets, key nutrients like vitamin D, creatine, and omega-3 fatty acids play crucial roles, influencing gene expression vital for muscle development and function.
Muscle health is a lifelong journey shaped by genetics, environment, and, critically, nutritional programming. Novel biomarkers, such as non-coding RNAs, hold promise for early sarcopenia detection in vulnerable groups, including obese or underweight older adults.
This Special Issue highlights the essential need for nutritional interventions that not only provide sufficient macro- and micronutrients but also positively influence the epigenetic landscape of muscle cells. These targeted strategies offer immense promise for optimizing musculoskeletal health, ultimately preventing sarcopenia and its associated functional decline.
Prof. Dr. Maria J. Martin
Guest Editor
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Keywords
- sarcopenia
- geriatric nutrition
- anabolic resistance
- sarcopenic obesity
- muscle health
- healthy aging
- frailty
- dietary and exercise interventions
- nutrition strategies for sarcopenia prevention
- nutritional supplements and sarcopenia
- polyphenols
- high-protein diet, leucine and HMB
- biomarkers
- inflammaging
- metabolic syndrome and aged muscle
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