Precision Nutrition in Pediatric Inflammatory Bowel Disease

Dear Colleagues,

Young children represent the fastest growing population worldwide regarding the incidence and prevalence of inflammatory bowel disease. Nutrition can be considered a simple, cost-effective treatment for thess kinds of pathologies, especially in children, but many gaps must be filled in order to understand how—and if—precise nutrition could improve the QoL of children affected by pediatric inflammatory bowel disease. The application of Precision Nutrition in the field of Inflammatory Chronic Bowel Disease is an emerging concept. Recently, the National Institute of Health (N.I.H.) launched the Strategic Plan for NIH Nutrition Research, aiming to research particular set of beliefs, ideas, or rules that referr to Inflammatory Bowel Disease in order to help medical doctors to solve this problem. The four main topics of this Special Issue are as follows: 1. Evaluation of evidence-based and rationally designed anti-inflammatory diets in RCTs (researchers from U.C.L.A. have recently designed an anti-inflammatory whole-food diet based on the exclusion of pro-inflammatory foods combined with anti-inflammatory phytonutrients and prebiotics). 2. Identification of biomarkers of responders and non-responders. 3. Dietary triggers of relapse. 4. In silicio personalized predictions of responses to diet. Collaboration on these different four steps could be possible in order to design and realize a Therapeutic Precision Nutrition for I.B.D. In conclusion, the need to understand the role of Precision Nutrition in pediatric Inflammatory Bowel Disease has to become a pillar for the future health of children, and we hope that this Special Issue will contribute to a better understanding of the state of the art of this new, safe, and cost-effective therapy.

Dr. Marco Bertini
Dr. Roberto Miniero
Dr. Valentina Talarico
Guest Editors

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