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Parenteral Nutrition in Chronic Intestinal Failure: Challenges, Innovations and Future Directions

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 20 May 2026 | Viewed by 3

Special Issue Editor


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Guest Editor
Internal Medicine and Clinical Nutrition, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy
Interests: clinical nutrition; malnutrition; artificial (enteral and parenteral) nutrition indications; monitoring and complications; obesity; nutritional follow-up after bariatric surgery; cachexia; sarcopenia; sarcopenic obesity; eating disorders; body composition
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Special Issue Information

Dear Colleagues,

It is our great pleasure to invite you to contribute to this upcoming Special Issue of Nutrients, entitled “Parenteral Nutrition in Chronic Intestinal Failure: Challenges, Innovations and Future Directions”.

Chronic intestinal failure (CIF) remains a major clinical challenge. Many specialists still do not know how to manage it, and it is often underestimated. Parenteral nutrition (PN) is a life-saving therapy for many of these patients, yet it also raises complex issues regarding long-term management, nutritional adequacy, and the prevention of complications.

This Special Issue aims to highlight recent advances and ongoing challenges in the field, with a focus on the following topics:

  1. The nutritional needs of patients with chronic intestinal failure and the clinical consequences of nutritional deficiencies;
  2. The correct management of vascular access devices for parenteral nutrition to prevent thrombotic and infectious complications;
  3. The impact of intestinal microbiota alterations and their interplay with nutritional and clinical outcomes;
  4. The role of preventive antithrombotic strategies in patients on long-term PN to minimize vascular complications, including the use of taurolidine;
  5. The psychological burden, anxiety, and quality of life of patients and caregivers;
  6. Emerging therapies aimed at reducing dependence on parenteral nutrition, including teduglutide.

By collating high-quality original research and comprehensive reviews, we hope to provide clinicians and researchers with an updated perspective on this rapidly evolving field and to keep the medical community fully engaged in optimizing care for patients with CIF.

We warmly invite you to submit your valuable work to this Special Issue and join us in advancing the knowledge and practice of parenteral nutrition for chronic intestinal failure.

Dr. Lidia Santarpia
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chronic intestinal failure (CIF)
  • home parenteral nutrition (HPN)
  • intestinal microbiota
  • teduglutide
  • quality of life
  • caregivers

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Published Papers

This special issue is now open for submission.
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