Nutrition Strategies for Brain Aging
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Neuro Sciences".
Deadline for manuscript submissions: 25 October 2026 | Viewed by 43
Special Issue Editor
Interests: Alzheimer; clinical neurosciences; EEG; MRI; psychiatry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The increase in average life expectancy is one of society’s major achievements. However, it is associated with a shift in the leading causes of morbidity and mortality from infectious diseases to non-communicable conditions and, in particular, mental disorders. WHO guidelines highlight that the correct intake of nutrients contributes to a robust immune system and lower risk for neurological and psychiatric disorders. Several studies indicate that the long-term consumption of a Mediterranean diet (rich in fruits, vegetables, and olive oil) favors better cognition in aged populations and patients with Parkinson’s disease (PD), Alzheimer’s disease (AD), and other types of dementia. In these cases, the available evidence has suggested that nutrition could delay the onset of the disease, and slows down its trajectory through changes in biochemical and epigenetic factors. Moreover, advances in our understanding of the mechanisms underlying the actions of macro- and micronutrients on the microbiota–gut–brain axis could allow for the development of new strategies focusing on brain function optimization and the prevention of neurodegenerative disorders. Similarly, dietary factors such as energy overload, skipping breakfast, unhealthy diet styles such as Western diet, an inflammation-prone diet, and high consumption of ultra-processed food are shown to increase the risk of depression in old age. This is also the case for nutritional imbalances such as inadequate intake of protein, polyunsaturated fatty acids, vitamins (folate and vitamin D), and minerals (iron and zinc). This Special Issue aims to provide a comprehensive overview of the role of nutrition in brain-aging-related pathologies, including molecular, epigenetic, and epidemiological evidence. Special interest will be paid to translational research that fills the gap between laboratory findings and clinical expressions of neurological and psychiatric disorders in old age.
Prof. Dr. Panteleimon Giannakopoulos
Guest Editor
Manuscript Submission Information
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Keywords
- brain aging
- diet
- mental disorders
- neurodegeneration
- nutrition
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