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How Dietary Components Affect Cognitive Function, Memory Performance and Mood?

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: 25 August 2024 | Viewed by 2533

Special Issue Editors


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Guest Editor
1. Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy
2. Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
Interests: supplement; vitamin D; depression; dementia; Alzheimer; aging; oxidative stress; inflammation
Special Issues, Collections and Topics in MDPI journals

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Co-Guest Editor
Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy
Interests: aging; geriatrics; nutrition; senescence; telomeres; telomerase; dementia; cognition; diabetes; metabolism
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nutrition plays a pivotal role in promoting overall well-being during the aging process. Specifically, a well-balanced and nutritious diet is crucial for reducing the risk of dementia and managing mood disorders. This Special Issue aims to explore the complex relationship between dietary choices and cognitive well-being, clarifying the impact of various dietary components on memory, cognitive function and mood. In this context, evidence shows that specific dietary patterns (such as Mediterranean diet) and nutrients (such as omega-3 fatty acids, antioxidants and vitamins) play a role in enhancing memory and the overall cognitive function.

The following are the relevant topics for this Special Issue that will elucidate the complex relationship between dietary choices and cognitive well-being:

•    The impact of nutrients on cognitive functions and mood; 
•    Cognitive function and different dietary patterns;
•    Mood modulation through nutrition; 
•    The impact of dietary habits during aging;
•    Intervention and prevention strategies. 

Prof. Dr. Patrizia Mecocci
Prof. Dr. Virginia Boccardi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aging
  • cognition
  • diet
  • intervention
  • memory
  • mood
  • nutrients
  • prevention
  • well-being

Published Papers (1 paper)

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Research

14 pages, 1350 KiB  
Article
Effects of Withania somnifera Extract in Chronically Stressed Adults: A Randomized Controlled Trial
by Srikanta Pandit, Amit K. Srivastav, Tapas K. Sur, Supriyo Chaudhuri, Yan Wang and Tuhin K. Biswas
Nutrients 2024, 16(9), 1293; https://doi.org/10.3390/nu16091293 - 26 Apr 2024
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Abstract
Background: Stress is a known causative factor in modulating cognitive health, which overall well-being and quality of life are dependent on. Long-term stress has been shown to disrupt the balance of the hypothalamic–pituitary–adrenal (HPA) axis. Adaptogens, such as Withania somnifera (ashwagandha), are commonly [...] Read more.
Background: Stress is a known causative factor in modulating cognitive health, which overall well-being and quality of life are dependent on. Long-term stress has been shown to disrupt the balance of the hypothalamic–pituitary–adrenal (HPA) axis. Adaptogens, such as Withania somnifera (ashwagandha), are commonly used in Ayurvedic medicine for stress relief and ameliorating HPA-axis dysfunction. The aim of this study was to support the role of a root and leaf water-extracted ashwagandha extract (WS) in stress reduction by confirming the lowest clinically validated dose for stress management (125 mg/day) in a dose-dependent clinical study in adults with self-reported high stress. Methods: An 8-week, randomized, double-blinded, placebo-controlled study to compare the effects of three different WS extract doses (125, 250 and 500 mg) was performed. A total of 131 adults were enrolled, and 98 were included in the final analysis. Attenuation of chronic stress was measured using the 14-item Perceived Stress Scale (PSS) and biochemical-related stress parameters. Results: We have shown that aqueous WS extract (roots and leaves) safely reduces mild to moderate chronic stress at doses of 125 mg, 250 mg, and 500 mg/day for 8 weeks. Conclusions: Our findings demonstrate the stress-reduction capabilities of this well-characterized aqueous extract of WS (root and leaf) at the low dose of 125 mg/day, in a dose-dependent manner, via the modulation of the HPA axis. Trial registration: This study was registered with the Clinical Trials Registry—India (CTRI) with the registration number: CTRI/2019/11/022100. Full article
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