Fructose Metabolism and Diabetes – Where Do We Stand Now?
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Diabetes".
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 8605
Special Issue Editor
2. Food and Nutrition Service Department, Fujita Health University Hospital, Toyoake 470-1192, Japan
Interests: molecular nutrition; carbohydrate intake and health; pathophysiology of young underweight women in Japan; carbohydarate response element binding protein
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Fructose is a monosaccharide with a higher protein glycolytic capacity than glucose that metabolizes faster than acetyl CoA due to the absence of rate-limiting enzymes such as glucokinase. It is also considered more toxic than glucose. Excessive sucrose intake is associated with obesity, hyperuricemia, type 2 diabetes, dyslipidemia, NAFLD, frailty, and cancer. Moreover, fructose has been thought to be metabolized in the liver, not in the small intestine. However, recent studies have shown that small amounts of fructose are completely converted to glucose, and its metabolites have been found in the small intestine. Furthermore, it has been shown that unabsorbed fructose is converted to acetic acid by intestinal bacteria, absorbed through the portal vein, and used for lipid synthesis. Therefore, when considering the mechanisms underlying fructose-induced fatty liver development, it is important to consider the role of the small intestine and even the intestinal microbiota in addition to the conventional liver. Furthermore, exogenous as well as endogenous fructose has been reported to cause renal damage.
For this Special Issue, we call for a wide range of original papers and review articles on the relationship between fructose intake and metabolic diseases, focusing on fructose metabolism in the gut, liver, gut microbiota, and kidneys.
Dr. Katsumi Iizuka
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- fructose
- gut microbiota
- fatty liver
- cancer
- kidney
- gut microbiota
- metabolic syndrome
- obesity
- diabetes mellitus
- dyslipidemia
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
