Special Issue "Non-Coding RNA and Intracellular Structures"
A special issue of Non-Coding RNA (ISSN 2311-553X).
Deadline for manuscript submissions: closed (31 March 2020).
Interests: lncRNAs; RNP complex; Cell organization by liquid phase separation
Interests: lncRNAs; nuclear structures; paraspeckles; animal models
Multiple non-coding RNAs (ncRNAs) can be found in various intracellular structures, where they perform regulatory functions by recruiting specific proteins, RNAs, and chromatin loci. Some of these ncRNAs are present in heterochromatins and regulate their formation and/or maintenance by recruiting specific epigenetic regulatory proteins to the site of their accumulation. Other ncRNAs act as structural scaffolds of intracellular bodies without membranes by sequestering a specific set of RNA-binding proteins that contain an intrinsically-disordered domain, which triggers the liquid–liquid phase transition or hydrogel formation under certain conditions. Other ncRNAs have been reported to preferentially interact with a non-classical binding partner, such as membrane-lipids. The accumulating evidence regarding the distribution and interaction partners of ncRNAs suggest that ncRNAs localized in intracellular structures arrange the formation of a specific microenvironment consisting of the ncRNAs and their binding proteins around the respective ncRNA molecules. This Special Issue on non-coding RNAs and intracellular structures aims to unravel the diverse roles of ncRNAs in the formation and regulation of RNA-related intracellular structures, especially focusing on the molecular mechanisms and the physiological consequences.
Prof. Tetsuro Hirose
Prof. Shinichi Nakagawa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Non-Coding RNA is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- non-coding RNA
- nuclear bodies
- RNP complex
- phase separation
- animal model