Dear Colleagues,

Hyperthermia is a medical procedure that has been used since the end of the 19th century for the treatment of solid tumors. It consists of heating cancer cells, which are more sensitive to temperature than healthy cells, to around 42 - 45°C. Since the 1980s, the combination of nanoparticles and external physical stimuli has made it possible to limit hyperthermia to the tumor area. This is called localized hyperthermia. Depending on the nature of the nanoparticles and the external physical stimulus, two types of localized hyperthermia treatments can be distinguished: (i) photothermal therapy, PTT, assisted by plasmonic nanoparticles (mainly gold) under near-infrared illumination, NIR, (in the 650-900 nm range); (ii) magnetic fluid hyperthermia (MFH) mediated by superparamagnetic nanoparticles (mainly iron oxides or ferrites) under alternating magnetic fields (AMFs). In both cases, the parameters that influence the photo or magneto-thermal response of the nanoparticles are size, shape or self-assembly. For gold nanoparticles, nanorods, nanostars or nanoshells are the shapes that have the best heating properties. For iron oxide nanoparticles, the three most promising systems are nanocubes, ferrite core–shell nanosystems and self-assemblies.

This Special Issue of Nanomaterials, entitled “Plasmonic and Magnetic Nanoparticles for Localized-Hyperthermia”, aims to highlight magnetic and plasmonic nanomaterials that allow heating properties to be increased in solution, in cellulo and in vivo. The study and understanding of synergistic effects in systems that combine magnetic and plasmonic nanoparticles will also be considered.

Dr. Lenaic Lartigue
Guest Editor

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• magnetic fluid hyperthermia
• photothermal therapy
• magnetic nanocube
• magnetic multicore nanoparticules
• gold nanoshell
• core–shell ferrite
• gold nanorods
• gold nanostar