Nanotechnology in Dentistry

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 2323

Special Issue Editor


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Guest Editor
Institute of Oral Science, Chung Shan Medical University, Taichung City 402, Taiwan
Interests: surface biofunctionalization; implant materials; antibacterial coating; bone graft substitute
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nanotechnology plays a vital role in current oral health, care, treatment and diagnosis. It is well recognized that nanotechnology uses nanoscale particles and surface features to fabricate new materials and devices whose physicochemical properties, biological functions and antibacterial effects are remarkably different from those of microparticles of the same composition. In today's dental field, nanotechnology has been used to develop nanoparticle fillers to improve the esthetic, mechanical and biological properties of resin-based composites. Nanoparticles can also promote hard tissue remineralization and be used in the diagnosis and treatment of oral cancer. The development of nanoscale self-assembled and self-healing materials for the replacement or repair of oral tissues has been another focus. Similarly, nanostructured and functionalized materials can be designed for pulp regeneration, or as scaffolds or carriers for regenerative dentistry. On the other hand, the treatment of biofilm-dependent oral diseases, such as dental caries and endodontic and periodontal diseases, has been an urgent problem. An example of a promising strategy is the development of antimicrobial nanomaterials, such as antimicrobial peptides. Coating or modification of the dental implant surface can enhance osseointegration and improve antibacterial activity through bimolecule delivery. Treatment techniques such as antimicrobial photodynamic therapy also require molecule-level photosensitive agents to debride the biofilm in peri-implant diseases.

Emerging nanotechnologies for exploiting tooth repair, treatment, mineralization, regeneration and diagnosis are constantly being pursued. In this Special Issue, we cordially invite review articles and research papers to present the current state of the art in nanodentistry that can enhance clinical use and treatment. In particular, topics of interest include, but are not limited to, the following:

  • Nanofillers;
  • Surface functionalization;
  • Self-assembly and self-healing;
  • Peptides;
  • Bone implants;
  • Regenerative dentistry;
  • Diagnostic nanodentistry;
  • Preventive nanodentistry;
  • Restorative nanodentistry.

Prof. Dr. Shinn-Jyh Ding
Guest Editor

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Keywords

  • coating
  • surface modification
  • peptide
  • filler
  • regenerative dentistry
  • resin-based composite
  • endodontics

Published Papers (2 papers)

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Research

20 pages, 2774 KiB  
Article
An Evaluation of Experimental Calcium Ion-Leachable Nanocomposite Glass Ionomer Cements
by Ioannis Tsolianos, Alexandros K. Nikolaidis, Elisabeth A. Koulaouzidou and Dimitris S. Achilias
Nanomaterials 2023, 13(19), 2690; https://doi.org/10.3390/nano13192690 - 30 Sep 2023
Viewed by 920
Abstract
Glass ionomer cements (GICs) are among the main restorative dental materials used broadly in daily clinical practice. The incorporation of clay nanoparticles as reinforcing agents is one potential approach to improving GIC properties. This study aims to investigate whether the incorporation of calcium-modified [...] Read more.
Glass ionomer cements (GICs) are among the main restorative dental materials used broadly in daily clinical practice. The incorporation of clay nanoparticles as reinforcing agents is one potential approach to improving GIC properties. This study aims to investigate whether the incorporation of calcium-modified clay (Ca-clay) nanoparticles in conventional GICs alters their structural characteristics, along with their physicochemical and mechanical properties. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) analyses were performed to assess the surface characterization of GIC nanocomposites, whereas a setting reaction was carried out via an attenuated total reflection Fourier transform infrared spectrometer (ATR-FTIR). A universal testing machine was used for compression tests, while calcium ion release was quantified using inductively coupled plasma optical emission spectrometry (ICP-OES). GIC composite groups reinforced with Ca-clay were found to release a fine amount of calcium ions (5.06–9.91 ppm), with the setting reaction being unaffected for low Ca-clay loadings. The median compressive strength of 3 wt% in the Ca-clay group (68.97 MPa) was nearly doubled compared to that of the control group (33.65 MPa). The incorporation of Ca-clay nanoparticles in GICs offers a promising alternative among dental restorative materials regarding their chemical and mechanical properties. Full article
(This article belongs to the Special Issue Nanotechnology in Dentistry)
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16 pages, 4364 KiB  
Article
Plasmonic Effect of Gold-Patchy Silica Nanoparticles on Green Light-Photopolymerizable Dental Resin
by Melinda Szalóki, István Csarnovics, Attila Bonyár, Ditta Ungor, Edit Csapó, András Sápi and Csaba Hegedűs
Nanomaterials 2023, 13(18), 2554; https://doi.org/10.3390/nano13182554 - 13 Sep 2023
Cited by 3 | Viewed by 1012
Abstract
A low ratio of polymerization is a major problem in resin-based composites. In this paper, the plasmonic effect of gold-covered silica nanoparticles on the physicochemical and mechanical properties of bisphenol A diglycidyl dimethacrylate (Bis-GMA), triethylene glycol dimethacrylate (TEGDMA) and urethane dimethacrylate (UDMA) green [...] Read more.
A low ratio of polymerization is a major problem in resin-based composites. In this paper, the plasmonic effect of gold-covered silica nanoparticles on the physicochemical and mechanical properties of bisphenol A diglycidyl dimethacrylate (Bis-GMA), triethylene glycol dimethacrylate (TEGDMA) and urethane dimethacrylate (UDMA) green light-photopolymerizable dental resin was investigated at an intensity of 1.4 mW/cm2 for 40 s. Transmission electron microscopy (TEM) showed silica of about 350 nm covered with 12–15 nm gold nanoparticles (Au NPs) at 100% nominal coverage. Five different concentrations of bare and patchy silica particles were used; in the latter composite, the calculated Au wt% were 0.0052 wt%, 0.0104 wt%, 0.0208 wt%, 0.04160 wt%, and 0.0823 wt%. The plasmon peak of patchy silica-filled nanocomposite overlapped with the absorption of Irgacure 784 photoinitiator and green LED light emission peak. The effect of plasmon-enhanced polymerization achieved with green light illumination was analyzed using diametral tensile strength (DTS), differential scanning calorimetry (DSC), surface plasmon resonance imaging (SPRi), and degree of conversion (DC) based on Raman spectroscopy. The values of the Au NP with 0.0208 wt% was found to be maximum in all the measured data. Based on our result, it can be concluded that the application of patchy silica particles in dental resin can improve the polymerization ratio and the mechanical parameters of the composite. Full article
(This article belongs to the Special Issue Nanotechnology in Dentistry)
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