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Extraction and Treatment Technologies of Bioactive Compounds from Natural Sources

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 1907

Special Issue Editor


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Guest Editor
Department of Food Technology and Nutrition, Mahasarakham University, Mahasarakham, Thailand
Interests: technologies for extraction; process and product development of functional foods; bioactive compounds

Special Issue Information

Dear Colleagues,

Research on bioactive compounds from natural sources has expanded over the last decade. This interest has been focused not only on new knowledge but also on commercial applications, including functional ingredients, cosmetics, dietary supplements, and functional food products.

Extraction is the crucial first step in the analysis of natural sources, since it is necessary to extract the desired chemical components from the materials for further separation and characterization. Treatment technologies also play significant roles in preserving or even enhancing the bioactive compounds. The effects of various treatments on the content and biological properties, as well as bioavailability, of bioactive compounds are the main concerns with respect to product development.

For this reason, this Special Issue of Molecules is focused on extraction and treatment technologies of bioactive compounds with potential uses as functional food ingredients, dietary supplements, and cosmetics. This will provide an overview of the current status and future perspectives of the manufacturing design of these highly valuable products.

Potential topics include, but are not limited to, the following:

  • Extraction methods and treatment technologies for bioactive compounds from natural sources;
  • Secondary metabolites, phenolic compounds, flavonoids, bioactive peptides, or other bioactive components.

This Special Issue titled “Extraction and Treatment Technologies of Bioactive Compounds from Natural Sources” will include a selection of recent research and current review articles about extraction methods and treatment technologies for bioactive compounds from natural sources. This Special Issue is particularly focused on articles describing new extraction and treatment technologies to recover/preserve/enhance bioactive compounds from different sources, bioactive properties, and applications as functional ingredients.

We cordially invite you to contribute original research papers or reviews to this Special Issue of Molecules.

Prof. Dr. Sirithon Siriamornpun
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

16 pages, 2330 KiB  
Article
Optimization of Ultrasound-Assisted Extraction of Yields and Total Methoxyflavone Contents from Kaempferia parviflora Rhizomes
by Wantanwa Krongrawa, Sontaya Limmatvapirat, Supachai Saibua and Chutima Limmatvapirat
Molecules 2022, 27(13), 4162; https://doi.org/10.3390/molecules27134162 - 29 Jun 2022
Cited by 6 | Viewed by 1629
Abstract
The major bioactive components of Kaempferia parviflora (KP) rhizomes, 3,5,7,3′,4′-pentamethoxyflavone (PMF), 5,7-dimethoxyflavone (DMF), and 5,7,4′-trimethoxyflavone (TMF), were chosen as the quantitative and qualitative markers for this plant material. In order to extract bioactive components (total methoxyflavones) from KP rhizomes, ultrasound-assisted extraction (UAE) was [...] Read more.
The major bioactive components of Kaempferia parviflora (KP) rhizomes, 3,5,7,3′,4′-pentamethoxyflavone (PMF), 5,7-dimethoxyflavone (DMF), and 5,7,4′-trimethoxyflavone (TMF), were chosen as the quantitative and qualitative markers for this plant material. In order to extract bioactive components (total methoxyflavones) from KP rhizomes, ultrasound-assisted extraction (UAE) was proposed as part of this study. Plackett–Burman design (PBD) and Box–Behnken design (BBD) were utilized to optimize the effects of UAE on extraction yields and total methoxyflavone contents in KP rhizomes. First, PBD was utilized to determine the effect of five independent variables on total yields and total methoxyflavone contents. The results indicated that the concentration of the extracting solvent (ethanol), the extraction time, and the ratio of solvent to solid were significant independent terms. Subsequently, BBD with three-level factorial experiments was used to optimize the crucial variables. It was discovered that the concentration of ethanol was the most influential variable on yields and total methoxyflavone contents. Optimum conditions for extraction yield were ethanol concentration (54.24% v/v), extraction time (25.25 min), and solvent-to-solid ratio (49.63 mL/g), while optimum conditions for total methoxyflavone content were ethanol concentration (95.00% v/v), extraction time (15.99 min), and solvent-to-solid ratio (50.00 mL/g). The relationship between the experimental and theoretical values was perfect, which proved that the regression models used were correct and that PBD and BBD were used to optimize the conditions in the UAE to obtain the highest yield and total methoxyflavone content in the KP rhizomes. Full article
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