Design and Synthesis of Chemical Probes for Epigenetic Modification Enzymes and Proteins

Dear Colleagues,

The last few decades have witnessed the tremendous progress of epigenetics. The ever-growing epigenetic landscape is tightly and precisely regulated by a group of epigenetics modification enzymes and proteins, many of which have been proposed as potential therapeutic targets for the treatment of diseases such as cancer, neurodegeneration, and metabolic disorders. Innovative chemical approaches are highly sought after for a better understanding of the biological functions of these enzymes and proteins. This Special Issue will provide a broad overview of the most recent progress in the discovery, design, and synthesis of novel chemical probes for epigenetic modifying enzymes and proteins. Contributions (including full papers, communications, and reviews) that report the development of new methodologies, small molecule probes, or techniques to reveal the physiological relevance of abovementioned targets are welcome.

Prof. Dr. Yana Cen
Guest Editor

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