Obesity and Neurodegeneration

Dear Colleagues,

Obesity is associated with increased intake of energy-dense foods and poor physical activity. Inactive lifestyles are becoming more prominent worldwide, leading to clinical, social, and monetary challenges. Individuals who suffer from obesity could understand how difficult to lose weight through physical activity and correct diet only.

The effect of obesity on brain function and cognition is quite known. However, research regarding the influence of obesity cerebral areas and the involved neurotransmission should be increased. The reason resides in an increasing number of overweight individuals that will potentially become obese in the next years. In any case, the increase in the number of elderly people from one side and the increase in the number of obese people from another side may lead to a demanding medical challenge in the next few decades.

The main goal of this Special Issue is to highlight different aspects of the linkage between obesity and neurodegeneration, publishing a series of papers that study the mechanisms at the basis of this possible connection. In this context, the effect of correct nutrition and lifestyle may represent crucial factors in overcoming obesity and consequently improve brain conservation among young and elderly people.

Therefore, this Special Issue particularly encourages original articles that evaluate the synthesis and the mechanisms of action of active molecules on obesity and interacts with neurodegeneration. It welcomes original articles or reviews that will correlate obesity, nutrition, lifestyles, and physical inactivity with neurodegenerative processes, and exploring the mechanisms involved in them.

Dr. Seyed Khosrow Tayebati
Prof. Dr. Daniele Tomassoni
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• synthesis
• mechanisms of action
• nutrition
• lifestyle
• physical activity
• obesity mechanisms
• inflammation
• cognition
• dementia
• neurodegenerative mechanisms