Special Issue "High Throughput Screening II"
Deadline for manuscript submissions: closed (15 July 2019).
Interests: translational research; high-throughput screening; assay development; laboratory automation
Interests: post-translational modification; ubiquitination; activity-based probes; enzymology; DNA damage tolerance; nucleic acid chemistry; high throughput screening; small molecule inhibitor; cancer, neurodegeneration
In the last decade, we have witnessed the increased popularity of high throughput screening (HTS) in academia for tool compound development and drug discovery. This has been largely fueled by the rapid developments at many fronts of biology, and the novel targets identified through these efforts. The creation of academic screening centers and the NIH Molecular Libraries Roadmap Initiative have spearheaded the effort and provided crucial infrastructural and technical support to many academic labs engaged in probe development and unravelment of fundamental biology using an HTS approach. With the continued growth of the academic drug discovery effort and the increased demands of high quality tool compounds, the interest in HTS will continue to increase among academic researchers. We thus would like to put together this Special Issue on HTS to highlight the most recent development in the many different fronts of HTS research, encompassing novel assay formats, new targets and screening technologies. We invite the submission of full articles and communications reporting recent work on biochemical, cell-based, phenotypic, and targeted screening. We also welcome timely reviews on the above topics and any other areas of HTS that will capture the interest and imagination of the HTS community.
We thank in advance for your contribution to this Special Issue on HTS.
Dr. Anton Simeonov
Prof. Zhihao Zhuang
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- high-throughput screening
- screening methods
- screening data analysis
- novel targets
- assay artifacts
- compound profiling
- assay development
- laboratory automation