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Special Issue "Biocatalysis in Organic Synthesis"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Green Chemistry".

Deadline for manuscript submissions: 31 March 2019

Special Issue Editors

Guest Editor
Dr. Gonzalo de Gonzalo

Universidad de Sevilla, Department of Organic Chemistry, Sevilla, Spain
Website | E-Mail
Interests: biocatalysis; asymmetric synthesis; organocatalysis; heterogeneous catalysis; biooxidations; cofactor regeneration; concurrent reactions; kinetic resolution; dynamic processes; hydrogen bond catalysts
Guest Editor
Dr. Fabricio R. Bisogno

Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina
Instituto de Investigaciones en Físico-Química de Córdoba (INFIQC), CONICET.
Interests: stereoselective synthesis; biocatalysis; artificial enzymatic cascades; redox processes; organosulfur and organoselenium chemistry; multicomponent reactions

Special Issue Information

Dear Colleagues,

The preparation of valuable chiral compounds requires the development of more efficient methodologies, in which selectivity and atom economy of the processes become the ‘evolutionary pressure’. Biocatalysis, i.e., the use of purified enzymes, cell free extracts or whole cells, as catalyst in organic processes, offers several advantages for the synthesis of high-added value materials. Thus, biocatalysts generally display exquisite selectivities while using mild and eco-friendly reaction conditions. Enzymatic reactions are economically feasible. Biocatalysis often face some drawbacks that hampered their complete application in organic methodologies, including low substrates concentrations or the need of expensive cofactor molecules for different types of reactions. In the last few years, several efforts have been devoted to overcoming these bottlenecks, including the preparation of immobilized biocatalysts, medium engineering with the use of different non-conventional media for biocatalyzed reactions, the development of efficient cofactor recycling systems, and even designing cascade reactions. In this Special Issue, we shall focus in the recent advances in the application of effective biocatalytic procedures in organic chemistry.

Dr. Gonzalo de Gonzalo
Dr. Fabricio R. Bisogno
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Asymmetric synthesis
  • Biocatalyzed processes
  • Stereoselectivity
  • Medium engineering
  • Immobilized biocatalysts
  • Dynamic enzymatic processes
  • Cofactor recycling
  • Enzymatic synthesis of APIs

Published Papers

This special issue is now open for submission.
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