Potential of Astaxanthin in Drug Development
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 457
Special Issue Editor
Interests: nanotechnology; lipid formulations; drug delivery; drug targeting; cellular models; animal models; oxidative stress; antioxidants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Astaxanthin, a powerful natural antioxidant extracted from marine organisms and microalgae, was shown to protect cells and tissues by maintaining cellular redox homeostasis and blocking the oxidative stress. Astaxanthin is proposed as therapeutic agent for the treatment and prevention of oxidative stress-related diseases such as cardiovascular pathologies, neurodegenerative disorders, diabetes and cancer. However, astaxanthin is a very sensitive unsaturated molecule that can be degraded by light, oxygen and temperature, leading to a decrease in its bioavailability and loss of its properties. Despite extensive evidence showing the role of astaxanthin on human health in the prevention and treatment of several pathologies, progress is needed in the development of formulations to stabilize and protect astaxanthin molecule before its therapeutic administration.
This Special Issue is intended to highlight recent research on astaxanthin drug development. Original research on chemical modifications of astaxanthin, inclusions and encapsulations of astaxanthin in nano / microparticles, pharmaceutical formulations, drug administration studies, adsorption / diffusion studies for oral or dermal administration, biological evaluations (in vitro, in vivo, clinical) and reviews to highlight the potential of astaxanthin in drug development are recommended to be presented in this Special Issue.
Dr. Graciela Pavon-Djavid
Guest Editor
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Keywords
- astaxanthin
- formulations
- chemical evaluation
- antioxidant activity
- nanoparticles
- diffusion studies
- oral administration
- biological activity
