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Special Issue "New Antibiotics from Natural Sources"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (1 July 2021).

Special Issue Editor

Dr. Nobuhiro Koyama
E-Mail Website
Guest Editor
Microbial Chemistry and Medicinal Research Laboratories, Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
Interests: natural products chemistry; chemical biology; metabolomics
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Natural sources have proven to be attractive sources of antibiotics due to their structural diversity and interesting biological activity. The definition of “antibiotic” was originally “an antibiotic is a chemical substance produced by micro-organisms, which has the capacity to inhibit the growth of and even to destroy bacteria and other micro-organisms”. After that, microbial compounds with various biological actions were discovered; therefore, the definition has extended to microbial compounds not only with antimicrobial action but also with antifungal action, antineoplastic action, immunosuppressive action, and lipid-lowering action, etc. However, the prevalence of the discovery of new antibiotics with novel structures has been declining in recent years, and such antibiotics are urgently needed. Meanwhile, the 2015 Nobel Prize, awarded to scientists that contributed to the discovery of an anti-parasitic drug lead “avermectin”, reminded us of the significance of and necessity of tackling this field. Additionally, the recent discovery of new antibiotics such as “teixobactin” (Nature, 2015) and “corbomycin” (Nature, 2020) has led to re-recognition of their excellent sources in antibiotics screening.

As Guest Editor of this Special Issue, I encourage researchers and scientists involved in this field to submit papers on new findings that may offer significant advances in the area.

Dr. Nobuhiro Koyama
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Antibiotics
  • Anti-microbial compounds
  • Anti-infectives
  • Mechanism of action
  • Target identification.

Published Papers

There is no accepted submissions to this special issue at this moment.
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