Design, Synthesis, and Biological Evaluation of Pyridone Derivatives
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 109
Special Issue Editor
Interests: natural product extraction; semisynthesis; synthesis; chromone derivatives; pyridone derivatives; domino reaction; cycloaddition
Special Issue Information
Dear Colleagues,
Pyridones (2-pyridones and 4-pyridones) are interesting frameworks for medicinal chemistry. They are widely distributed in natural products, and their synthesis, especially considering 2-pyridones and derivatives, has drawn much attention from researchers. As one of the major representative members of the N-heterocyclic family, natural pyridones and their synthetic derivatives displayed a wide range of biological activities, including antibacterial, antifungal, antiviral, antidiabetic, anticancer, etc. Therefore, the present Special Issue of Molecules is dedicated to original research and review articles that cover the latest findings (from 2000 up to now) about the techniques for their extraction, semisynthesis, synthesis, and their biological applications.
Topics of interest for this Special Issue include, but are not restricted to, the following:
- Synthetic methodologies for 2-pyridone and 4-pyridone derivatives, allowing the pyridone core diversification.
- Procedures for natural pyridones and derivatives extraction.
- Modification of natural pyridones to access more active compounds.
- Biological activities related to the pyridone core.
Dr. Ata Martin Lawson
Guest Editor
Manuscript Submission Information
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Keywords
- pyridones
- design and synthesis
- extraction
- semisynthesis
- reactivity
- fused-pyridones
- biological activities
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