Special Issue "Herbal Medicine in Cardiovascular Diseases Prevention and Therapy"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (31 December 2019).
Interests: natural products; lipids; hypertension; diabetes; pharmacogenetics; ethnic differences of drug responses.
Interests: medcine; blood pressure; superoxide dismutase; cardiac myocytes; endothelin-1; gene expression; reactive oxygen species
Cardiovascular disease is the leading cause of death throughout the world. The prevalence may have plateaued in some developed countries, but it is still increasing in many developing countries. Atherosclerotic cardiovascular disease is the major underlying cause, with the risk factors of hypertension, hyperlipidaemia, and diabetes mellitus being highly prevalent in most populations. Increasing rates of obesity have fueled the epidemic of diabetes and contributed to increases in blood pressure and lipid disorders. Many effective drugs are available to treat hypertension, and in recent years, several new classes of agents to manage hyperglycaemia have been introduced. The glucagon-like peptide-1 (GLP1) receptor agonists and sodium-glucose transport protein 2 (SGLT2) inhibitors have shown reductions in cardiovascular events in patients with diabetes. These new classes of agents have origins in the natural substances exendin-4 and phlorizin. Exciting developments have occurred in the field of hyperlipidaemia with the discovery of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the development of monoclonal antibodies and other treatments to inhibit this. It is now feasible to treat most of the major cardiovascular risk factors effectively, but this is a long way from becoming a reality, in part due to the high cost of some of these novel therapies. The treatment of heart failure has also improved with the availability of the angiotensin receptor-neprilysin inhibitor, valsartan/sacubitril, but the prevalence of heart failure is still increasing, resulting in considerable morbidity and mortality. Herbal medicines have been used for many types of heart disease for centuries. Obvious examples are digitalis from Digitalis purpurea and other foxglove species and salicylates from willows such as Salix alba. A multitude of other herbal medicines have been used or investigated for cardiovascular diseases.
This Special Issue on “Herbal Medicine in Cardiovascular Diseases Prevention and Therapy” has been designed to include original research and reviews on herbal medicines that are established or under investigation for the management of cardiovascular diseases and the major risk factors for coronary heart disease and other cardiovascular conditions.
Prof. Brian Tomlinson
Prof. Paul Chan
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Cardiovascular diseases
- Coronary heart disease
- Heart failure
- Herbal medicines