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Open AccessReview

Effects of Bilberry Supplementation on Metabolic and Cardiovascular Disease Risk

by 1,*,† and 2,*,†
1
School of Health Sciences, Caritas Institute of Higher Education, Hong Kong SAR 999077, China
2
Faculty of Medicine, Macau University of Science & Technology, Macau 853, China
*
Authors to whom correspondence should be addressed.
The authors contribute equally to the manuscript.
Molecules 2020, 25(7), 1653; https://doi.org/10.3390/molecules25071653
Received: 19 March 2020 / Accepted: 1 April 2020 / Published: 3 April 2020
(This article belongs to the Special Issue Herbal Medicine in Cardiovascular Diseases Prevention and Therapy)
Metabolic syndrome is a cluster of interrelated conditions that is associated with an increased risk of cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Oxidative stress may impair normal physiological functions, leading to various illnesses. T2DM is considered to be associated with increased oxidative stress, inflammation, and dyslipidemia, which may play a significant role in the development of cardiovascular complications, cancer and vision loss through cataracts and retinopathy. While conventional therapies are a cornerstone for the management of the major risk factors of metabolic syndrome, increasing antioxidant defense by increasing intake of antioxidant-rich foods may improve long term prospects in CVD, obesity and T2DM. Bilberry (Vaccinium myrtillus L.) is one of the richest natural sources of anthocyanins which give berries their red/purple/blue coloration. Anthocyanins are powerful antioxidants and are reported to play an important role in the prevention of metabolic disease and CVD as well as cancer and other conditions. This review focuses on the potential effects of bilberry supplementation on metabolic and cardiovascular risk factors. Although there is evidence to support the use of bilberry supplementation as part of a healthy diet, the potential benefits from the use of bilberry supplementation in patients with T2DM or CVD needs to be clarified in large clinical trials. View Full-Text
Keywords: bilberry; antioxidant; anti-inflammatory; cardiovascular disease; hypoglycemic effect; type 2 diabetes bilberry; antioxidant; anti-inflammatory; cardiovascular disease; hypoglycemic effect; type 2 diabetes
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MDPI and ACS Style

Chan, S.W.; Tomlinson, B. Effects of Bilberry Supplementation on Metabolic and Cardiovascular Disease Risk. Molecules 2020, 25, 1653. https://doi.org/10.3390/molecules25071653

AMA Style

Chan SW, Tomlinson B. Effects of Bilberry Supplementation on Metabolic and Cardiovascular Disease Risk. Molecules. 2020; 25(7):1653. https://doi.org/10.3390/molecules25071653

Chicago/Turabian Style

Chan, Sze W.; Tomlinson, Brian. 2020. "Effects of Bilberry Supplementation on Metabolic and Cardiovascular Disease Risk" Molecules 25, no. 7: 1653. https://doi.org/10.3390/molecules25071653

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