Novel Scaffold: From Synthesis to Therapeutic Applications
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 384
Special Issue Editors
Interests: drug discovery; medicinal chemistry; heterocyclic compounds; enzyme inhibition activity; antiproliferative activity; anticonvulsant activity; antimicrobial study
Interests: chemical biology; natural products; cancer biology; tumor metabolism; signaling pathways
Special Issues, Collections and Topics in MDPI journals
Interests: dendrimers; organic synthesis; protective group chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue, entitled “Novel Scaffold: From Synthesis to Therapeutic Applications”, will focus on the synthesis and therapeutic approaches of novel bioactive molecules against different diseases.
During the last decade, diseases caused by pathogens such as bacteria, fungus and viruses have posed serious threats to human health. Undesirable side effects, a lack of selectivity, systemic toxicity and the emergence of multidrug resistance are the major drawbacks associated with current medicines. Therefore, the development of new drugs by focusing on rational design is an urgent clinical need to improve the therapeutic efficacy of bioactive molecules.
This Special Issue aims to outline all of the approaches regarding the rational design, synthesis and therapeutic potential of novel scaffolds for the development of more reliable, target-based, pharmacologically active drugs.
Dr. Samreen Gul Khan
Dr. Azhar Rasul
Dr. Jørn Bolstad Christensen
Guest Editors
Manuscript Submission Information
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Keywords
- bioactive compounds
- drug design
- biological activity
- medicinal chemistry
- enzyme inhibition
- drug discovery
- organic synthesis
- structure–activity relationship (SAR)
- anticonvulsant activity
- antidiabetic activity
- anticancer activity
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