Asymmetric Synthesis and Catalysis of Chiral Molecules
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 171
Special Issue Editor
Special Issue Information
Dear Colleagues,
Chiral molecules are central to pharmaceuticals, agrochemicals, and advanced functional materials, where differences between enantiomers critically influence efficacy, safety, and performance. Asymmetric synthesis and catalysis remain among the most powerful strategies to access enantioenriched structures. This Special Issue welcomes cutting-edge advances across transition-metal catalysis, organocatalysis, and biocatalysis for enantioselective C–C and heteroatom bond formations; cascade and multicomponent reactions; kinetic resolution, dynamic kinetic resolution, and deracemization; and applications to natural products, drug candidates, and chiral functional materials. We particularly encourage contributions on catalyst/ligand design, novel chiral scaffolds, reaction mechanistic and computational studies of stereoinduction, as well as sustainable and scalable processes (e.g., green solvents, earth-abundant metals, photocatalysis and electrocatalysis, and flow chemistry). We also welcome studies at the interface of chiral separation and analytical methodologies that enable process development and quality control. Both original research articles and authoritative reviews are invited, with the aim of highlighting fundamental insights and practical solutions that accelerate the discovery and production of chiral molecules.
Dr. Yangxue Liu
Guest Editor
Manuscript Submission Information
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Keywords
- asymmetric synthesis
- asymmetric catalysis
- chiral catalyst
- chiral functional materials
- chiral separations
- chiral resolution
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