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Special Issue "Breakthroughs in Drug Discovery and Delivery in Oncology"

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 397

Special Issue Editors

Department of Molecular Science and Nanosystems, Università Ca' Foscari Venezia, Venice, Italy
Interests: cancer therapy; signaling pathways; precision medicine; drug delivery system
Special Issues, Collections and Topics in MDPI journals
Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy
Interests: medicinal chemistry; drug design; ligand–protein binding, molecular interactions; molecular modeling; hit identification; lead optimization
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the time of precision medicine, most of the efforts are dedicated to developing new drugs that target specific proteins to precisely kill cancer cells. As recognized by Robert A. Weinberg and Douglas Hanahan in the seminal paper “Hallmarks of Cancer: The Next Generation”, the tumor microenvironment is a key element in the tumorigenesis process. The identification of ligands able to modulate the activity of specific targets in cancer and supporting stroma cells is becoming one of the most studied research fields in drug discovery. In the oncology field, since many potential drug targets were identified and novel technologies were developed in the early drug discovery steps, the detection of target modulators has become a common goal for medicinal chemists and chemical biologists. In addition, bio- and nanomaterials are being applied to improve the pharmacokinetic parameters.

This Special Issue aims to provide a forum for the dissemination of:

a) The latest information on novel approaches for the identification and optimization of target modulators;

b) Research studies reporting the design, synthesis, and biological evaluation of potentially active ligands;

c) Strategies for drug nano-formulations and their therapeutic applications.

Dr. Flavio Rizzolio
Prof. Dr. Tiziano Tuccinardi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Drug design
  • Drug discovery
  • Drug delivery
  • Molecular modeling
  • Nanostructured materials

Published Papers

There is no accepted submissions to this special issue at this moment.
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