Total Synthesis of Natural Products and Their Analogues
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: closed (30 April 2025) | Viewed by 823
Special Issue Editor
Interests: medicinal chemistry; natural products total synthesis; asymmetric synthesis; bioactive natural products; polymeric materials; anticancer treatments; synthesis from biowaste-derived materials; isotopically labelled materials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The diversity of natural products, whether from terrestrial, marine, or microbial origin, continues to challenge synthetic chemists. Synthesis is frequently conducted to confirm the molecular structures of isolated natural products, and to challenge chemists developing new synthetic methodologies or exploring the massive array of biological activities natural products can induce. With natural products commonly found as single enantiomers, asymmetric approaches are frequently utilized to define the stereochemistry and to determine, or confirm, the absolute configurations of natural products. In this regard, total synthesis plays an important role as a means to achieve the unambiguous assignment of chemical structure. Additionally, total synthesis provides access to material for biological testing which may not be available from the natural source itself. Furthermore, total synthesis develops methods that can then be used to access unnatural analogues, often with the aim of improving biological properties.
Prof. Dr. David Barker
Guest Editor
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Keywords
- total synthesis
- natural products
- asymmetric synthesis
- structure determination
- synthetic methodology
- analogue synthesis
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