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Nanomaterials for the Detection of Biomolecules

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 967

Special Issue Editors


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Guest Editor
Centre of Polymer and Carbon Materials, Polish Academy of Sciences, Zabrze, Poland
Interests: X-ray diffraction; energy harvesting; ferroelectrics; ceramic nanoparticles; polymer matrix composites; carbon–polymer composites; ceramic–polymer composites
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Institute of Physics–Center for Science and Education, Silesian University of Technology, Krasińskiego 8, 4 40-019 Katowice, Poland
Interests: nanocrystals; nanogenerators; energy harvesting; ferroelectrics; photovoltaic devices
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Institute of Physics of the Czech Academy of Sciences, Prague, Czech Republic
Interests: eletronalytical chemistry

Special Issue Information

Dear Colleagues,

In recent decades, much attention has been focused on the synthesis and application of nanomaterials, especially in the detection of various molecules to improve our health and safety. Suitable and highly sophisticated synthesis methods, such as top-down and bottom-up approaches, have allowed researchers to obtain nanomaterials with tunable characteristics, such as size, shape, and electrical and thermal properties. The same concept has been employed to fabricate hybrid nanodevices based on various nanomaterials with different properties.

The results obtained in this field have given rise to a class of novel devices with great potential for detecting various molecules, including bio-based and environmental ones.

This Special Issue seeks to outline the recent innovations and state of the art in the design, synthesis, and characterization of nanomaterial-based systems for the detection of bio-based and environmental molecules.

Dr. Marcin Godzierz
Dr. Krystian Mistewicz
Dr. Rene Pfeifer
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanomaterials
  • electrochemistry
  • biological sensors
  • gas sensors
  • synthesis
  • molecule detection

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Published Papers (1 paper)

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Review

30 pages, 2541 KB  
Review
Methods for Conjugating Antibodies with Quantum Dots
by Pavel Sokolov, Alexander Knysh, Irina Kriukova, Pavel Samokhvalov and Yury V. Kistenev
Molecules 2025, 30(19), 3999; https://doi.org/10.3390/molecules30193999 - 6 Oct 2025
Viewed by 709
Abstract
Nanomaterials are increasingly used in the development of detection systems for various disease biomarkers as tools for reliable early diagnosis, which is a key factor in reducing mortality and increasing treatment effectiveness. The use of quantum dot–antibody conjugates allows for optical detection of [...] Read more.
Nanomaterials are increasingly used in the development of detection systems for various disease biomarkers as tools for reliable early diagnosis, which is a key factor in reducing mortality and increasing treatment effectiveness. The use of quantum dot–antibody conjugates allows for optical detection of various disease markers in biological fluids, tissues, and individual cells with high sensitivity and specificity. The sensitivity and specificity of detection are determined not only by the outstanding optical properties of fluorescent quantum dots but also by the type of antibodies used for binding target analytes and the methods of their conjugation with quantum dots. This review deals with methods of site-specific and site-nonspecific conjugation of quantum dots with antibodies, including full-length and single-domain antibodies, as well as antibody fragments, with a special focus on their structural features and active moieties used for binding to their targets. The review includes examples of successful applications of quantum dot–conjugated antibodies in diagnosis, environment monitoring, and food safety assessment. We also discuss the prospects of further research in this field, including new conjugation methods and issues related to the stability and specificity of probes. The review provides a comprehensive analysis of the current methods and achievements in antibody conjugation from the viewpoint of subsequent analyte detection, highlighting the importance of further research for improving the existing technologies. Full article
(This article belongs to the Special Issue Nanomaterials for the Detection of Biomolecules)
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