Targeting Cell Signaling Pathways in Drug Discovery
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: 31 October 2026 | Viewed by 29
Special Issue Editor
Interests: medicinal chemistry; anticancer drugs; nutraceuticals; multi-target agents; bioactive products; natural extracts; antioxidant activity; anti-inflammatory activity; cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We invite you to contribute to this Special Issue, entitled “Targeting Cell Signaling Pathways in Drug Discovery”. The global rise in non-communicable diseases (NCDs) is a major health challenge, fueled significantly by unhealthy lifestyles. Despite substantial research efforts, the incidence of infectious, cardiovascular, inflammatory, neurodegenerative, and cancer diseases continues to grow relentlessly. The current drugs used in therapies often face significant limitations, including numerous side effects due to low specificity, non-optimal pharmacokinetic profiles and drug resistance.
Considering this critical scenario, the development of new synthetic and natural molecules with improved pharmaceutical and pharmacokinetic profiles, as well as with the ability to interfere with specific key cellular targets involved in the development and progression of the main NCDs, is urgently needed.
This Special Issue will address these important challenges, welcoming the submission of original research papers or review articles that detail the design and synthesis of new synthetic or natural compounds able to interfere with significant cellular pathways of pharmaceutical interest.
Dr. Jessica Ceramella
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- targeted therapy
- non-communicable diseases
- enzymes
- synthetic compounds
- natural extracts
- molecular modeling
- chemically modified drugs
- cellular key targets
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