Research on Discovery, Bioactivity, and Mechanism of Natural Cyclopeptides
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 254
Special Issue Editors
Interests: natural products; cyclopeptide discovery; cyclopeptide-based bioactivity and mechanism; new target; tumor pharmacology
Special Issue Information
Dear Colleagues,
Natural cyclopeptides (NCPs) are a promising class of organic compounds that consist of peptides formed from amino acids arranged in a cyclic ring structure. While most NCPs are composed of 4 to 10 amino acids, some may contain dozens of amino acids. These cyclopeptides are typically isolated from natural resources such as plants, microorganisms, and invertebrate animals. NCPs possess unique structures and exhibit various therapeutic activities, including anthelmintic, ACE inhibitory, microtubule inhibitory, anti-tumor, anti-fungal, antimalarial, and platelet aggregation inhibitory activities. Recent research has focused on exploring the numerous beneficial effects of NCPs, and some have been successfully developed as bioactive products. Advances in visualization techniques, chemistry, molecular biology, and bioinformatics have accelerated research in this field.
In this Special Issue, our aim is to highlight recent studies on NCPs that feature new discoveries, new functions and new technologies. We believe that this Special Issue is a relevant and timely publication, and we look forward to receiving your contributions. More specifically, we are seeking original research articles, communications, and reviews that cover the following topics:
- Discovery of new bioactive cyclopeptides in natural resources;
- Qualitative and quantitative analyses of significant cyclopeptides in natural resources;
- New strategies or approaches for the discovery of natural cyclopeptides;
- Novel methods for the structural characterization of natural cyclopeptides;
- Gene mining and biosynthesis of natural cyclopeptides;
- New bioactivities and mechanisms of natural cyclopeptides;
- Biological functions and applications of natural cyclopeptides.
Dr. Zhe Wang
Dr. Xinya Hemu
Guest Editors
Manuscript Submission Information
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Keywords
- natural cyclopeptides
- isolation and identification
- bioactivity
- mechanisms
- new strategies
- gene mining
- biosynthesis
- biological application
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