Design and Synthesis of Antiviral Drugs Targeting Enzymes of Emerging RNA Viruses
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 170
Special Issue Editors
Interests: molecular virologist; antiviral development; antiviral drugs
Special Issues, Collections and Topics in MDPI journals
Interests: computational chemist; antiviral design, identification, development; antiviral drugs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, evidence supporting the need for pandemic preparedness against emerging viral pathogens has become striking.
Particular efforts are needed against emerging RNA viruses that possess a high pathologic potential and represent the major source of new possible spillover events.
The effective management of emerging viral infections has a narrow window of opportunity for first-line mitigation measures. In this respect, the availability of ready-to-use small-molecule therapeutics represents an essential tool.
To achieve this, the need to exploit the viral enzymatic functions as possible drug targets is the first and most promising strategy. In this field, the role of computational techniques is gaining attention, increasing the success rate of screening campaigns, helping to dissect the mode of interaction between compounds and their targets, and helping to design improved chemical scaffolds. In this Special Issue, we aim to collect the most advanced studies on viral enzyme-targeting small molecules to increase the knowledge and boost the effort in relation to identifying new promising drug candidates.
Dr. Angela Corona
Dr. Antonio Lupia
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antivirals
- RNA viruses
- viral replication
- drug design
- enzyme inhibitors
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
