Journal Menu► ▼ Journal Menu
Journal Browser► ▼ Journal Browser
Special Issue "Microbe–Host Interactions: From Infection to Innate Immunity Aspects"
Deadline for manuscript submissions: 29 February 2020.
2. Life Sciences Department, Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, UK
Interests: cryo X-ray tomography; microbiology; innate immunity; bacteria phagocytocis; fungal pathogenesis; host-pathogen interactions
Microbe–host interactions are defined as the mechanisms employed by microbes to sustain themselves within hosts in the presence of the host immune responses. The outcome of the above interplay can be as diverse as the organisms involved, including obligatory or accidental interactions which result into various states like symbiosis, commensalism or disease. The initial host–microbe interaction involves the recognition of conserved microbial components known as the pathogen-associated molecular patterns (PAMPs) by the host pattern recognition receptors (PRRs). Following PAM–PRR binding, signal transduction initiates a complex cascade of cellular reactions, leading to an early host response that not only contributes to microbial elimination but also provides an essential stimulus to the adaptive immune response.
This Special Issue will focus on the innate immune signaling pathways within in vivo and ex vivo research models, such as cell lines, invertebrates and rodent models, which define the interaction frame between the host and pathogenic or non-pathogenic microbial strains including bacteria, fungi or viruses. Contributions will range from the molecular and cellular level, studying the infection routes employed by microbes to invade the host, to the organismal and population level, investigating pathogen persistence and colonization and host homeostatic imbalance factors.
Recent advances and modern tools, such as next-generation sequencing, metagenomics and advanced microscopy methods like super-resolution microscopy, have provided a glimpse into intimate details of the functional and molecular interface between microbial strains and their hosts.
Dr. Ilias Kounatidis
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Host–microbe interaction
- Fungal pathogenesis
- Innate immunity
- Immune signaling pathways
- Next-generation sequencing
- Super-resolution microscopy