Marine Microbial Systems: From Molecular Mechanisms to Biotechnological Innovations

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 3

Special Issue Editor

State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, China
Interests: bacterial cell wall; peptidoglycan; lipoprotein; atomic force microscopy; antimicrobial resistance; microbial physiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The marine realm harbors Earth's most phylogenetically diverse microbial communities, with current estimates suggesting that >90% of oceanic microorganisms remain undiscovered or uncharacterized. These microbial systems have evolved extraordinary adaptive strategies to thrive across extreme gradients of pressure, temperature, and salinity, while playing fundamental roles in global carbon/nitrogen cycling and ecosystem resilience. Their unique biological features—from piezophilic enzymes to bioactive secondary metabolites—represent an untapped frontier for both basic science and applied biotechnology. 

This Special Issue will highlight cutting-edge research on marine microbial systems, with particular focus on the following:

  • Novel adaptive mechanisms at molecular/genomic levels;
  • Functional biodiversity spanning uncultured phyla;
  • Ecosystem-scale interactions and biogeochemical impacts;
  • Evolutionary innovation in extreme environments. 

We welcome contributions addressing fundamental mechanistic studies as well as applied research in areas including the following:

  • Enzyme discovery and engineering: Extremozymes, metabolic pathways, structural adaptation;
  • Drug discovery: Antimicrobial/anticancer compounds, biosynthetic gene clusters;
  • Environmental solutions: Bioremediation, carbon sequestration, plastic degradation;
  • Omics technologies: Single-cell genomics, meta-transcriptomics, spatial metabolomics;
  • Synthetic biology: Chassis development, heterologous expression systems. 

The Special Issue aims to bridge the gap between basic research and translational applications, showcasing how molecular understanding of marine microorganisms can drive innovations in medicine, agriculture, energy, and environmental sustainability.

Dr. Hainan Su
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • marine microorganisms
  • functional enzymes
  • bioactive secondary metabolites
  • bio-manufacturing
  • bio-pharmaceutical
  • bio-agriculture
  • environmental governance

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Published Papers

This special issue is now open for submission.
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