Host Versus Pathogen: Candida Infections, Immune Response and Therapy Perspectives

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 53

Special Issue Editors

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Guest Editor
Department of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy
Interests: innate immunity to fungal infections; Candida; mucosal candidiasis; microbiota and mycobiota; fungal and bacterial biofilm; antifungal strategies

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Guest Editor
Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK
Interests: C. albicans; Candida; candidiasis

Special Issue Information

Dear Colleagues,

Candida spp. can be detected on the mucosal surfaces of around 50–70% of healthy individuals but it can also induce a wide range of cutaneous, mucosal and systemic infections every year under predisposing conditions, such us breaches in intestinal barriers, dysbiosis and immunodeficiency.

Candida albicans is considered the main human fungal pathogen, but recently there has been an increase in infections induced by non-albicans Candida species. One of the species causing the greatest global concern is Candida auris, an emerging multidrug-resistant strain, first described in Japan in 2009, that has recently been included in the group of the critical priority fungal pathogens by the WHO.

The interplay between Candida spp. and the host immune system is fundamental to resolving the infection and, after initial recognition, innate and adaptive immune cells as well as non-immune cells, contribute to the antifungal response.

This Special Issue of Microorganisms aims to provide a collection of articles highlighting recent discoveries and advances in the field of Candida study, from the perspectives of both the host and the pathogen. Studies regarding potential new therapeutic approaches and those on the role of the interactions with other microorganisms during the infection process are also welcome.

As Guest Editors of this Special Issue, we invite you to submit research articles, reviews, and short communications covering a range of Candida infections and the host immune response they elicit.

We look forward to receiving your contributions.

Dr. Eva Pericolini
Dr. Elena Roselletti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Candida spp.
  • candidiasis
  • mucosal infection
  • invasive infection
  • innate immune response
  • adaptive immune response
  • drug resistance
  • anti-Candida therapies

Published Papers

This special issue is now open for submission.
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