Integrated Optical, Electrochemical, and Electrical Biomicrofluidics

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 624

Special Issue Editors


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Guest Editor
Institute of Materiobiology, College of Science, Shanghai University, Shanghai 200444, China
Interests: nucleic acid self-assembly technology; DNA nano-biosensors; develop DNA nano-carriers and hydrogels for drug delivery and disease treatment

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Guest Editor
State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China
Interests: microfluidics; droplet; deterministic lateral displacement; wearable devices; bacteria detection; on-chip imaging; POCT device
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Institutional Center for Shared Technologies and Facilities, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China
Interests: micro/nano device processing; MEMS; graphene field-effect transistors (GFETs); biosensor system

Special Issue Information

Dear Colleagues,

A biosensor can detect the presence of analytes in a sample and consists of a receptor system, a transducer, and a readout system. In recent years, with the rapid development of micro/nano fabrication and microfluidics technologies, biosensors for assessing health, including POC technologies, have made great progress, owing to their selectivity, sensitivity, stability, and portability.

With functions like optical, electrochemical, and electrical characterization and with manipulation or/and detection abilities combined with microfluidics or other biosensing platforms, one can achieve fast, accurate, real-time, in situ, and multiplexed detections. These technologies are gradually being applied in many academic and industrial fields, such as healthcare, biochemistry, life sciences, food, water quality, and so on. This Special Issue will provide an opportunity for researchers to publish their original achievements related to integrated optical, electrochemical, and electrical biomicrofluidics.

This Special Issue welcomes both original research and review articles that address the following non-exhaustive list of topics:

  • On-chip sensor fabrication, integration (optical, electrical, etc.) and packaging;
  • Processing and fabrication of micro- and nano-devices;
  • Modification of biosensing interfaces;
  • Micro/nano biosensors/actuators;
  • Microfluidic chips and systems integration;
  • Silicon photonics;
  • Electrochemical microfluidics;
  • Bioimpedance microfluidics.

Dr. Lihua Wang
Dr. Shilun Feng
Prof. Xiuli Gao
Guest Editors

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Published Papers (1 paper)

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Review

28 pages, 16516 KiB  
Review
Recent Advances in Microfluidics-Based Monitoring of Waterborne Pathogens: From Isolation to Detection
by Guohao Xu, Gaozhe Cai, Lijuan Liang, Jianxin Cheng, Lujie Song, Rui Sun, Feng Shen, Bo Liu, Shilun Feng and Jin Zhang
Micromachines 2025, 16(4), 462; https://doi.org/10.3390/mi16040462 - 14 Apr 2025
Viewed by 414
Abstract
Waterborne pathogens seriously threaten human life and can cause diarrhea, gastrointestinal disorders, and more serious systemic infections. These pathogens are usually caused by contaminated water sources that contain disease-causing microorganisms, such as bacteria, viruses, and parasites, which cause infection and disease when they [...] Read more.
Waterborne pathogens seriously threaten human life and can cause diarrhea, gastrointestinal disorders, and more serious systemic infections. These pathogens are usually caused by contaminated water sources that contain disease-causing microorganisms, such as bacteria, viruses, and parasites, which cause infection and disease when they enter the human body through drinking water or other means. Due to the wide range of transmission routes and the high potential risk of waterborne pathogens, there is an urgent need for an ultrasensitive, rapid, and specific pathogenic microorganism monitoring platform to meet the critical monitoring needs of some water bodies’ collection points daily monitoring needs. Microfluidics-based pathogen surveillance methods are an important stage towards automated detection through real-time and multi-targeted monitoring, thus enabling a comprehensive assessment of the risk of exposure to waterborne pathogens and even emerging microbial contaminants, and thus better protection of public health. Therefore, this paper reviews the latest research results on the isolation and detection of waterborne pathogens based on microfluidic methods. First, we introduce the traditional methods for isolation and detection of pathogens. Then, we compare some existing microfluidic pathogen isolation and detection methods and finally look forward to some future research directions and applications of microfluidic technology in waterborne pathogens monitoring. Full article
(This article belongs to the Special Issue Integrated Optical, Electrochemical, and Electrical Biomicrofluidics)
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