Special Issue "Next Generation Paper-based Devices for Analytical Applications"

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "C:Chemistry".

Deadline for manuscript submissions: 31 January 2020.

Special Issue Editor

Dr. Dionysios C. Christodouleas
E-Mail Website
Guest Editor
Department of Chemistry, University of Massachusetts Lowell, Lowell, MA 01845, USA
Tel. +1-978-934-5382; Fax: +1-978-934-3013
Interests: low-cost diagnostics; bioanalysis; advanced materials

Special Issue Information

Dear Colleagues,

Paper and other cellulosic materials (e.g., nitrocellulose) have been the building materials for several low-cost paper-based devices (e.g., test strips, lateral flow tests, paper-based analytical devices) that have the potential to decentralize and revolutionize chemical and biochemical analysis. In the last decade, scientists across the world set the foundations of this technology (i.e., invented several fabrication techniques, explored a number of different detection modes), and we all witnessed its rapid development to one of the most active fields of analytical chemistry. A large number of research studies have proven the possible applications of this technology from disease diagnostics to environmental monitoring and from specialized tests to diagnose rare diseases to devices for quality monitoring in chemical industry. At present, hundreds of research groups are working on the development of the next generation of paper-based devices and paper-based devices for various sensing applications. This Special Issue seeks to host a limited number of original research papers that describe new paper-based devices, new applications of paper-based devices in chemical and biochemical analysis, and a few review articles that describe the recent progress in the area of paper-based devices.

I am looking forward to your contributions.

Dr. Dionysios C. Christodouleas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • paper-based analytical devices
  • test strips
  • lateral flow tests
  • paper diagnostics

Published Papers (1 paper)

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Research

Open AccessArticle
Microfluidic Time-Delay Valve Mechanism on Paper-Based Devices for Automated Competitive ELISA
Micromachines 2019, 10(12), 837; https://doi.org/10.3390/mi10120837 - 30 Nov 2019
Abstract
Paper-based technologies have been drawing increasing attentions in the biosensor field due to their economical, ecofriendly, and easy-to-fabricate features. In this paper, we present a time-delay valve mechanism to automate a series of procedures for conducting competitive enzyme-linked immunosorbent assay (ELISA) on a [...] Read more.
Paper-based technologies have been drawing increasing attentions in the biosensor field due to their economical, ecofriendly, and easy-to-fabricate features. In this paper, we present a time-delay valve mechanism to automate a series of procedures for conducting competitive enzyme-linked immunosorbent assay (ELISA) on a paper-based device. The mechanism employs a controllable time-delay valve, which has surfactants to dissolve the hydrophobic barriers, in a fluid pathway. The valves can regulate the liquid and sequentially deliver the sample flow for automating ELISA procedures in microchannels. Competitive ELISA is achieved in a single step once the sample, or small molecule pesticide (e.g., Imidacloprid), is applied onto the paper-based device with a comparable sensitivity to plate-based competitive ELISA. The results further demonstrate the appositeness of using paper-based devices with the valve designs for on-the-go ELISA detection in agriculture and biomedical applications. Full article
(This article belongs to the Special Issue Next Generation Paper-based Devices for Analytical Applications)
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