Electrochemical Biosensors and Bioelectronic Microdevices for Point-of-Care and Wearable Applications

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B1: Biosensors".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 118

Special Issue Editors


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Guest Editor
Department of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai 980-8579, Japan
Interests: biosensor; electrochemical; POCT

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Guest Editor
1. Advanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology, Photonics Center, Osaka University, 2-1 Yamadaoka, Suita 565-0871, Osaka, Japan
2. SANKEN-The Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Suita 567-0047, Osaka, Japan
Interests: nanobiotechnology; advanced biosensor; bioMEMS; cell based device; biosensors for IoT
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Special Issue Information

Dear Colleagues,

Electrochemical biosensors have undergone remarkable innovation in recent years, driven by advances in nanomaterials, surface engineering, microfluidic integration, and low-power electronics. These technologies enable the highly sensitive, rapid, and selective detection of biochemical targets across a variety of complex environments, ranging from clinical diagnostics and environmental monitoring to food safety and wearable/implantable health assessment. With their intrinsic advantages—simple instrumentation, miniaturization compatibility, and quantitative output—electrochemical biosensors continue to play a pivotal role in bridging fundamental sensing science with real-world applications.

This Special Issue aims to highlight recent progress, emerging strategies, and future perspectives in electrochemical biosensing. We welcome contributions that address innovations in electrode materials, bio-recognition interfaces, signal transduction mechanisms, wireless data acquisition, and scalable device architectures. Studies demonstrating practical applications, field validation, and translational potential are particularly encouraged.

The scope of this Special Issue includes, but is not limited to, the following topics:

  • Sensor Platforms: Novel electrode architectures, nanomaterial-enhanced interfaces, flexible/printed electronics, microfluidic or wearable platforms, and wireless or IoT-integrated systems.
  • Signal Transduction & Analysis: Electrochemical detection strategies (amperometry, voltammetry, EIS, ECL, PEC, etc.), noise reduction approaches, multiplexed detection, and AI-assisted signal interpretation.
  • Biorecognition & Surface Engineering: Aptamers, enzymes, antibodies, molecularly imprinted polymers, antifouling coatings, and interfacial design for enhanced sensitivity, selectivity, and stability.
  • Applications: Point-of-care testing, environmental and food analysis, organophosphorus compounds and heavy metal detection, physiological monitoring (sweat, saliva, and ISF), and next-generation wearable/implantable biosensing systems.

We seek original research articles, reviews, communications, and perspectives that will contribute to advancing the science and technology of electrochemical biosensors across various disciplines. We look forward to receiving your submissions for this Special Issue.

Dr. Shuto Osaki
Prof. Dr. Eiichi Tamiya
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrochemical biosensors
  • nanomaterials
  • aptamer-based sensing
  • enzymatic and immune sensing
  • electrochemical impedance spectroscopy (EIS)
  • voltammetry and amperometry
  • electrochemiluminescence (ECL)
  • microfluidic and wearable platforms
  • point-of-care testing
  • surface engineering
  • wireless and IoT-enabled sensing
  • bio-battery
  • environmental and clinical diagnostics
  • microneedles 

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Published Papers

This special issue is now open for submission.
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