Microrheology with Optical Tweezers

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 1491

Special Issue Editor


E-Mail Website
Guest Editor
Division of Biomedical Engineering, James Watt School of Engineering, Advanced Research Centre, University of Glasgow, Glasgow G11 6EW, UK
Interests: rheology; microrheology; metrology; biophysics; biomedical engineering

Special Issue Information

Dear Colleagues,

I am pleased to introduce this Special Issue , titled "Microrheology with Optical Tweezers", which focuses on the intersection of microrheology and optical tweezers (OTs). Since their development in the 1970s, optical tweezers have transformed biophysical research by enabling precise nano-scale force and displacement measurements. Their application in microrheology—studying material flow at micron-length scales—has significantly advanced our understanding of complex biological materials that traditional methods cannot analyse. This issue explores the methodologies, challenges, and progress in using optical tweezers to measure tracer particle trajectories in various media, revealing the frequency-dependent viscoelastic properties of these materials. By examining both active and passive microrheology techniques, this collection aims to address their current challenges and to refine methodologies for more accurate and consistent future studies.

Whether you are a researcher contributing new findings or a reader keen on the latest developments, this issue provides valuable insights and fosters further innovation. I hope it serves as a valuable resource for your work.

Dr. Manlio Tassieri
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • optical tweezers
  • rheology
  • microrheology
  • metrology
  • biophysics
  • biomedical engineering

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

36 pages, 8597 KiB  
Review
Microrheology: From Video Microscopy to Optical Tweezers
by Andrea Jannina Fernandez, Graham M. Gibson, Anna Rył and Manlio Tassieri
Micromachines 2025, 16(8), 918; https://doi.org/10.3390/mi16080918 - 8 Aug 2025
Viewed by 511
Abstract
Microrheology, a branch of rheology, focuses on studying the flow and deformation of matter at micron length scales, enabling the characterization of materials using minute sample volumes. This review article explores the principles and advancements of microrheology, covering a range of techniques that [...] Read more.
Microrheology, a branch of rheology, focuses on studying the flow and deformation of matter at micron length scales, enabling the characterization of materials using minute sample volumes. This review article explores the principles and advancements of microrheology, covering a range of techniques that infer the viscoelastic properties of soft materials from the motion of embedded tracer particles. Special emphasis is placed on methods employing optical tweezers, which have emerged as a powerful tool in both passive and active microrheology thanks to their exceptional force sensitivity and spatiotemporal resolution. The review also highlights complementary techniques such as video particle tracking, magnetic tweezers, dynamic light scattering, and atomic force microscopy. Applications across biology, materials science, and soft matter research are discussed, emphasizing the growing relevance of particle tracking microrheology and optical tweezers in probing microscale mechanics. Full article
(This article belongs to the Special Issue Microrheology with Optical Tweezers)
Show Figures

Figure 1

Back to TopTop