Interplay between Nutrient and Metabolic Signaling in Cell Identity

Dear Colleagues,

High-throughput analysis has deepened our understanding on the metabolic flux and pathways required for cellular proliferation, energy production, and homeostasis. Recent advances have highlighted the contribution of metabolites as signaling molecules influencing the genome and epigenome of cells.

The metabolic programming of a cellular state represents a fine balance between the intrinsic needs and the constraints imposed by the extrinsic conditions. Systemic nutrition and diet can affect the environment within tissues and organisms and modulate nutrient availability and utilization by cells, and on the other hand, the cellular metabolic state convey changes within its environment. This two-way metabolic communication has deep implications for cell identity and can potentially be modulated for the design of improved therapeutic strategies.

Therefore, this Special Issue of Metabolites will be dedicated to publishing current advances on the interplay between nutrient and metabolic signaling in cell identity, self-renewal, plasticity, cell signaling, and cell to cell communication, with important implications for cancer and regeneration in aging and disease. Manuscripts dealing with other challenging issues are also desired.

Dr. Sandrina Nóbrega-Pereira
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.